Gastric Cancer
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 15, 2003; 9(7): 1404-1408
Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1404
Spiral CT in gastric carcinoma: Comparison with barium study, fiberoptic gastroscopy and histopathology
Feng Chen, Yi-Cheng Ni, Kai-Er Zheng, Sheng-Hong Ju, Jun Sun, Xi-Long Ou, Man-Hua Xu, Hao Zhang, Guy Marchal
Feng Chen, Kai-Er Zheng, Sheng-Hong Ju, Jun Sun, Department of Radiology, Zhongda Hospital, 87 Dingjiaqiao Road, Nanjing 210009, Jiangsu Province, China
Xi-Long Ou, Man-Hua Xu, Department of Digestive Diseases, Zhongda Hospital, 87 Dingjiaqiao Road, Nanjing 210009, Jiangsu Province, China
Feng Chen, Yi-Cheng Ni, Hao Zhang, Guy Marchal, Department of Radiology, University Hospital, Herestraat 49, B-3000 Leuven, Belgium
Author contributions: All authors contributed equally to the work.
Supported by ECR 2000-EAR-ECR Research & Education Fund Fellowship Grant
Correspondence to: Professor Yi-Cheng Ni, Department of Radiology, University Hospital, Herestraat 49, B-3000 Leuven, Belgium. yicheng.ni@med.kuleuven.ac.be
Telephone: +32-16-345940 Fax: +32-16-343765
Received: March 12, 2003
Revised: March 24, 2003
Accepted: April 11, 2003
Published online: July 15, 2003
Abstract

AIM: To evaluate spiral computed tomography (CT) including virtual gastroscopy for diagnosis of gastric carcinoma in comparison with upper gastrointestinal series (UGI), fiberoptic gastroscopy (FG) and histopathology.

METHODS: Sixty patients with histologically proven gastric carcinoma (54 advanced and 6 early) were included in this study. The results of spiral CT were compared with those of UGI and FG. Two observers blindly evaluated images of spiral CT and UGI and video recording of FG with consensus in terms of diagnostic confidence with a five-point scale. Sensitivities of lesion detection, Borrmann's classification of spiral CT, UGI and FG, as well as the accuracy of TNM staging of spiral CT were determined by comparing them to surgical and histological findings.

RESULTS: The lesion detection rate was 98% (59/60), 95% (57/60) and 98% (59/60) for spiral CT, UGI and FG, respectively. There were no statistical differences in the detection sensitivity among the three techniques (P > 0.05). For the sensitivity in Borrmann's classification, spiral CT was higher than that of UGI (P = 0.025) and similar to that of FG (P > 0.05). The accuracy of spiral CT in staging the gastric carcinoma was 76.7%. Six cases of early gastric carcinoma were all detected by spiral CT as well as FG.

CONCLUSION: Spiral CT is equivalent to UGI and FG in the detection of gastric carcinoma, and superior to UGI but similar to FG in the Borrmann's classification of advanced gastric carcinoma. Spiral CT is more valuable than FG in the staging of gastric carcinoma.

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