Case Report
Copyright ©The Author(s) 2003. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 15, 2003; 9(4): 878-880
Published online Apr 15, 2003. doi: 10.3748/wjg.v9.i4.878
Primary biliary cirrhosis and ulcerative colitis: A case report and review of literature
Wen-Bin Xiao, Yu-Lan Liu
Wen-Bin Xiao, Yu-Lan Liu, Department of Gastroenterology, People’s Hospital, Peking University, Beijing 100044, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Wen-Bin Xiao, Department of Gastroenterology, People’s Hospital, Peking University, Beijing 100044, China. hhxwb@263.net
Telephone: +86-10-68314422 Ext 5726 Fax: +86-10-68318386
Received: November 26, 2002
Revised: December 18, 2002
Accepted: December 25, 2002
Published online: April 15, 2003
Abstract

AIM: To summarize the characteristics of patients suffered from primary biliary cirrhosis associated with ulcerative colitis.

METHODS: To report a new case and review the literature.

RESULTS: There were 18 cases (including our case) of primary biliary cirrhosis complicated with ulcerative colitis reported in the literature. Compared with classical primary biliary cirrhosis, the patients were more often males and younger similar. The bowel lesions were usually mild with proctitis predominated. While ulcerative colitis was diagnosed before primary biliary cirrhosis in 13 cases, the presentation of primary biliary cirrhosis was earlier than that of ulcerative colitis in our new case reported here. The prevalence of primary biliary cirrhosis among patients of ulcerative colitis was almost 30 times higher than in general population.

CONCLUSION: Association of primary biliary cirrhosis with ulcerative colitis is rare. It should be considered in the differential diagnosis of hepatobiliary disease in patients with ulcerative colitis, and vice versa.

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