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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 14, 2026; 32(38): 121060
Published online Oct 14, 2026. doi: 10.3748/wjg.121060
Letter to the Editor: Endoscopic transparent caps for non-variceal upper gastrointestinal bleeding - more than just a one trick pony
Ippei Tanaka, Douglas Motomura, Neal Shahidi
Ippei Tanaka, Douglas Motomura, Neal Shahidi, Department of Medicine, University of British Columbia, Vancouver V5Z 1M9, British Columbia, Canada
Douglas Motomura, Neal Shahidi, Digestive Health Centre, St Paul’s Hospital, Vancouver V6Z 1Y6, British Columbia, Canada
Author contributions: Tanaka I, Motomura D and Shahidi N contributed to this paper; Shahidi N designed the overall concept and outline of the manuscript; Tanaka I, Motomura D, and Shahidi N contributed to the writing, and editing of the manuscript.
AI contribution statement: No artificial intelligence tools were used in the preparation of this manuscript.
Conflict-of-interest statement: Tanaka I and Motomura D have no conflicts of interest to declare. Shahidi N reports speaker’s honoraria from Pharmascience, Boston Scientific, and Takeda Pharmaceuticals, and research support from ERBE Elektromedizin GmbH. The authors declare no other conflicts of interest related to this manuscript.
Corresponding author: Neal Shahidi, MD, Assistant Professor, Department of Medicine, University of British Columbia, 770-1190 Hornby Street, Vancouver V5Z 1M9, British Columbia, Canada. nealshahidi@gmail.com
Received: March 16, 2026
Revised: May 25, 2026
Accepted: June 9, 2026
Published online: October 14, 2026
Processing time: 175 Days and 1.9 Hours
Abstract

Endoscopic transparent caps (ETC) are an essential component for endoscopic submucosal dissection and third space endoscopy; however, evidence for their role in non-variceal upper gastrointestinal bleeding (NVUGIB) remains limited. Herein, we describe the technical application of ETC and appraise the literature on their role for NVUGIB including the recent multi-centre retrospective evaluation by Küçükdemirci et al highlighting that ETC are a readily available and low-cost adjunct which may improve procedural efficacy and reduce transfusion requirements.

Keywords: Endoscopy; Hemostasis; Non-variceal upper gastrointestinal bleeding; Transparent cap; Ulcer bleeding; Transfusion

Core Tip: Endoscopic transparent caps (ETC) may facilitate hemostasis in non-variceal upper gastrointestinal bleeding (NVUGIB) by improving visualization and scope tip stability. Recent evidence, including a multi-centre retrospective study, suggests ETC-assisted endoscopy may improve procedural efficiency and reduce transfusion requirements. Given their simplicity, low cost, and widespread availability, ETC represent a practical adjunct during endoscopic hemostasis for NVUGIB. However, further well-designed studies are needed to clarify their optimal use and clinical impact.

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