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Artificial intelligence-assisted endoscopists improve the detection rate of high-risk gastric lesions: A propensity score-matched retrospective study
Jia-Xiu Ying, Si-Yan Yan, Xin-Yu Fu, Yi-Jing Zhou, Jing-Jing Zhou, Yan Yang, Xian-Bin Zhou, Zhen-Zhen Wang, Shao-Wei Li, Li-Na Fang, Xin-Li Mao
Jia-Xiu Ying, Xin-Li Mao, School of Medicine, Shaoxing University, Shaoxing 312000, Zhejiang Province, China
Jia-Xiu Ying, Xin-Li Mao, Taizhou Hospital of Zhejiang Province, Shaoxing University, Linhai 317000, Zhejiang Province, China
Si-Yan Yan, Department of Gastroenterology, The Affiliated Hospital of Jiaxing University, Jiaxing 314000, Zhejiang Province, China
Xin-Yu Fu, Department of Gastroenterology, Dalian Medical University, Dalian 116000, Liaoning Province, China
Yi-Jing Zhou, Jing-Jing Zhou, Xian-Bin Zhou, Zhen-Zhen Wang, Shao-Wei Li, Xin-Li Mao, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Jing-Jing Zhou, Xian-Bin Zhou, Zhen-Zhen Wang, Shao-Wei Li, Xin-Li Mao, Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Jing-Jing Zhou, Xian-Bin Zhou, Zhen-Zhen Wang, Shao-Wei Li, Xin-Li Mao, Institute of Digestive Disease, Taizhou Hospital Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Yan Yang, Taizhou Hospital of Zhejiang Province, Zhejiang University, Linhai 317000, Zhejiang Province, China
Li-Na Fang, Endoscopy Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China
Co-first authors: Jia-Xiu Ying and Si-Yan Yan.
Co-corresponding authors: Li-Na Fang and Xin-Li Mao.
Author contributions: Ying JX and Yan SY contributed equally to this article, they are the co-first authors of this manuscript; Ying JX, Yan SY, Fu XY, and Mao XL conceived and designed the study; Ying JX, Yan SY, Fu XY, Zhou YJ, and Yang Y participated in the data analysis, writing, and editing; Ying JX, Yan SY, Fu XY, Zhou YJ, Zhou JJ, Yang Y, Zhou XB, Wang ZZ, Li SW, Fang LN, and Mao XL performed validation and editing; Fang LN and Mao XL contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors have read and approved the final manuscript.
AI contribution statement: We used DeepL to help with translation and language polishing. We wrote every section ourselves. For parts of the Abstract, Introduction, Discussion, and Conclusion, we first drafted the content in Chinese and then used DeepL to help translate and polish the language. After that, we carefully reviewed and revised all the AI-assisted text to make sure the scientific content was accurate. We used DeepL for translation and language polishing in some parts of the manuscript. However, we did not use any AI tools for data analysis, and DeepL was only used to refine the language, not to help with writing the content itself. We designed the study, analyzed the data, and interpreted the results entirely on our own without any AI assistance. We created all the images and figures ourselves, without using any AI generation tools.
Supported by the “Pioneer” and “Leading Goose” R&D Program of Zhejiang, No. 2025C02139; the Medical Science and Technology Project of Zhejiang Province, No. 2024KY1788; the Program of Taizhou Science and Technology Grant, No. 22ywb09, No. 23ywa33, No. 23ywa35, and No. 23ywb03; and the Open Project Program of Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, No. 21SZDSYS01.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Taizhou Hospital of Zhejiang Province, approval No. K20240936.
Informed consent statement: The ethics committee has exempted the informed consent of the patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Statistical code, and dataset available from the corresponding author at
maoxl@enzemed.com. Participants was not obtained consent but the presented data are anonymized and risk of identification is low.
Corresponding author: Xin-Li Mao, MD, PhD, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, No. 150 Ximen Street, Linhai 317000, Zhejiang Province, China.
maoxl@enzemed.com
Received: December 8, 2025
Revised: January 29, 2026
Accepted: February 26, 2026
Published online: June 7, 2026
Processing time: 171 Days and 21.4 Hours
