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Randomized Controlled Trial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2025; 31(36): 110583
Published online Sep 28, 2025. doi: 10.3748/wjg.v31.i36.110583
Application of Meridian flow injection acupoint application combined with transcutaneous electrical acupoint stimulation in patients undergoing gastroenteroscopy
Xian Hong, Xiao-Yan Wu, Qing-Li Xu
Xian Hong, Xiao-Yan Wu, Qing-Li Xu, Center for General Practice Medicine, Department of Gastroenterology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China
Xian Hong, Xiao-Yan Wu, Qing-Li Xu, Department of Nursing, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China
Author contributions: Hong X, Wu XY, Xu QL, designed the study; Hong X, Wu XY, Xu QL, conducted investigations and research, provided software and conducted data organization; Hong X, Wu XY, and Xu QL analyzed the data and wrote a paper; All authors have read and approved the final version of the manuscript.
Supported by Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project, No. 2023ZL230.
Institutional review board statement: The research was reviewed and approved by Zhejiang Provincial People’s Hospital, No. 235.
Clinical trial registration statement: This study has not yet been registered with clinical trials.
Informed consent statement: All research participants or their legal guardians provided written informed consent prior to study registration.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CONSORT 2010 statement: I have read the CONSORT 2010 statement and the manuscript has been written and revised based on the CONSORT 2010 statement.
Data sharing statement: No other data available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Yan Wu, Chief Nurse, Department of Nursing, Hangzhou Medical College, No. 299 Jingbin Road, Gaobu Street, Yuecheng District, Hangzhou 312003, Zhejiang Province, China. ddyyzzmm88@163.com
Received: June 10, 2025
Revised: July 15, 2025
Accepted: August 27, 2025
Published online: September 28, 2025
Processing time: 100 Days and 23.4 Hours
Abstract
BACKGROUND

Although gastroscopy is a commonly used diagnostic and therapeutic technique, postoperative gastrointestinal dysfunction is prone to occur. Traditional Chinese medicine theory suggests that postoperative gastrointestinal disorders are related to spleen and stomach weakness. This study hypothesizes that the combination of acupoint application at the Ziwu Liuzhu acupoint and percutaneous acupoint electrical stimulation can promote postoperative gastrointestinal function recovery and alleviate stress reactions.

AIM

To investigate the effects of acupoint application of Ziwu Liuzhu combined with percutaneous acupoint electrical stimulation on postoperative gastrointestinal function recovery and stress response in patients undergoing gastrointestinal endoscopy surgery.

METHODS

A total of 120 patients who underwent gastroscopy surgery were selected and treated between October 2024 and January 2025. This study used a stratified block randomization method, and then allocated groups using computer-generated random number sequences (SAS 9.4 software). The groups were divided into two groups: A control group of 60 patients who received routine postoperative intervention measures, and an observation group of 60 patients who received acupuncture point application combined with transcutaneous acupoint electrical stimulation therapy. The therapeutic effects were compared after 3 days of treatment.

RESULTS

The mean time of first defecation was 3.20 ± 1.04 days, the mean first eating time was 2.55 ± 0.72 days, and the mean length of hospital stay was 5.57 ± 0.09 days (P < 0.05) after treatment. Gastrin levels were found to be (161.15 ± 16.75) pg/mL, norepinephrine (125.53 ± 17.78) pg/mL, cortisol (142.16 ± 19.55) μg/L, aldosterone (51.14 ± 5.39) pg/mL demonstrated superiority in comparison to the control group (P < 0.05). Conversely, the observation group exhibited superior outcomes, with an 93.33% success rate as opposed to the control group's 75.00%, and an overall satisfaction rate of 91.67% as compared to the control group's 68.33%. Moreover, the postoperative complication rate in the observation group was 16.67%, significantly lower than the 38.33% rate observed in the control group (P < 0.05).

CONCLUSION

The combination of percutaneous acupoint electrical stimulation in gastroscopy patients has been demonstrated to be both highly safe and effective. The benefits of this approach include the promotion of postoperative gastrointestinal function, the reduction of stress response, the attainment of optimal results, and the enhancement of patient satisfaction.

Keywords: Meridian flow injection acupoint application; Acupoint application; Transcutaneous electrical acupoint stimulation; Gastroscopy; Gastrointestinal function; Stress response

Core Tip: The article focuses on the application effect of Meridian flow injection acupoint application combined with transcutaneous acupoint electrical stimulation (TAES) in patients undergoing gastroenteroscopic surgery. When compared with conventional postoperative interventions, it was found that Meridian flow injection acupoint application combined with TAES could significantly shorten the time to first bowel movement, feeding time and hospital stay, improve gastrointestinal hormone levels, reduce stress response, improve patient satisfaction and reduce the incidence of complications. The trial confirmed the safety and efficacy of this combination therapy.