Cost-effectiveness of transient elastography for liver fibrosis screening in Thai patients with diabetes mellitus
Chayanis Kositamongkol, Pichaya Tantiyavarong, Alissa Ratanatawan, Pimsiri Sripongpun, Prawej Mahawithitwong, Prawat Kositamongkol, Surasak Saokaew, Pochamana Phisalprapa
Chayanis Kositamongkol, Pichaya Tantiyavarong, Department of Clinical Epidemiology, Faculty of Medicine, Thammasat University, Pathum Thani 10120, Pathum Thani, Thailand
Chayanis Kositamongkol, Pochamana Phisalprapa, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Krung Thep Maha Nakhon, Thailand
Alissa Ratanatawan, Department of Community Medicine and Family Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 10120, Pathum Thani, Thailand
Pimsiri Sripongpun, Gastroenterology and Hepatology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hatyai 90110, Songkhla, Thailand
Prawej Mahawithitwong, Prawat Kositamongkol, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Krung Thep Maha Nakhon, Thailand
Surasak Saokaew, Department of Pharmaceutical Care, School of Pharmaceutical Sciences, University of Phayao, Phayao 56000, Phayao, Thailand
Surasak Saokaew, Center of Excellence in Bioactive Resources for Innovative Clinical Applications, Chulalongkorn University, Bangkok 10330, Krung Thep Maha Nakhon, Thailand
Surasak Saokaew, Unit of Excellence on Clinical Outcomes Research and Integration (UNICORN), School of Pharmaceutical Sciences, University of Phayao, Phayao 56000, Phayao, Thailand
Co-corresponding authors: Pichaya Tantiyavarong and Pochamana Phisalprapa.
Author contributions: Tantiyavarong P and Phisalprapa P contributed equally to this study as co-corresponding authors; Kositamongkol C was responsible for the conceptualization, data curation, formal analysis, investigation, methodology, project administration, resources, validation, visualization, writing - original draft, and writing - review & editing; Tantiyavarong P was responsible for the conceptualization, formal analysis, methodology, project administration, validation, visualization, and writing - review & editing; Ratanatawan A was responsible for the conceptualization, methodology, supervision, validation, and writing - review & editing; Sripongpun P was responsible for the conceptualization, formal analysis, methodology, project administration, validation, visualization, writing - original draft, and writing - review & editing; Mahawithitwong P was responsible for the conceptualization, data curation, investigation, validation, and writing - review & editing; Kositamongkol P was responsible for the conceptualization, data curation, investigation, validation, and writing - review & editing; Saokaew S was responsible for the conceptualization, methodology, supervision, validation, and writing - review & editing; Phisalprapa P was responsible for the conceptualization, data curation, formal analysis, funding acquisition, investigation, methodology, project administration, resources, supervision, validation, visualization, and writing - review & editing.
Supported by Faculty of Medicine Siriraj Hospital, Mahidol University; Faculty of Medicine, Thammasat University; and University of Phayao and Thailand Science Research and Innovation Fund, No. 5017/2567.
Institutional review board statement: This study was approved by the Ethical Committee of Faculty of Medicine Siriraj Hospital, Mahidol University (Certificate of Approval No. Si 990/2023) and the Human Research Ethics Committee of Thammasat University (Medicine; Certificate of Approval No. 124/2024).
Clinical trial registration statement: This study is not a clinical trial involving human subjects; therefore, it was not registered in any Clinical Trial Registry.
Informed consent statement: The need for informed consent was waived owing to the retrospective nature of the study.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: This article and its Supplementary Information files include all the data generated or analyzed during this study.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Pochamana Phisalprapa, MD, PhD, Associate Professor, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Rd., Siriraj, Bangkok Noi, Bangkok 10700, Krung Thep Maha Nakhon, Thailand.
pochamana.phi@mahidol.ac.th
Received: June 5, 2025
Revised: July 2, 2025
Accepted: August 1, 2025
Published online: August 28, 2025
Processing time: 83 Days and 20.3 Hours
