Metabolic dysfunction-associated fatty liver disease and low muscle strength: A comment

Abstract

The diagnosis of non-alcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated fatty liver disease only on the basis of laboratory parameter score such as Hepatic Steatosis Index which includes liver enzymes, gender, basal metabolic index, and presence of diabetic mellitus is not sufficient to exclude other causes of deranged liver enzymes especially medications and autoimmune related liver diseases. As the guideline suggests ultrasound is the preferred first-line diagnostic procedure for imaging of NAFLD, as it provides additional diagnostic information and the combination of biomarkers/scores and transient elastography might confer additional diagnostic accuracy and evident from previous similar studies too.

Keywords: Non-alcoholic fatty liver disease; Metabolic dysfunction associated fatty liver disease; Low muscle strength; Hepatic Steatosis Index; Letter to the editor

Core Tip: Combining imaging modalities along with laboratory parameter-based scores increases the diagnostic yield of non-alcoholic fatty liver disease, and helps in the exclusion of the other secondary causes.