Transjugular intrahepatic portosystemic shunt: A promising therapy for recompensation in cirrhotic patients

doi:10.3748/wjg.v30.i16.2285

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Apr 28, 2024 (publication date) through Feb 27, 2026

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Gastroenterol. Apr 28, 2024; 30(16): 2285-2286
Published online Apr 28, 2024. doi: 10.3748/wjg.v30.i16.2285

Transjugular intrahepatic portosystemic shunt: A promising therapy for recompensation in cirrhotic patients

Ya-Ni Jin, Wei Zhang

Ya-Ni Jin, Wei Zhang, Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210000, Jiangsu Province, China

Author contributions: Jin YN wrote the letter; Zhang W revised the letter.

Conflict-of-interest statement: All the authors declare that they have no competing interests.

Corresponding author: Wei Zhang, MD, PhD, Department of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 321 Zhongshan Road, Nanjing 210000, Jiangsu Province, China. kimmysai@126.com

Received: January 16, 2024
Peer-review started: January 16, 2024
First decision: February 26, 2024
Revised: March 7, 2024
Accepted: April 2, 2024
Article in press: April 2, 2024
Published online: April 28, 2024
Processing time: 101 Days and 2 Hours

Abstract

This is a retrospective study focused on recompensation after transjugular intrahepatic portosystemic shunt (TIPS) procedure. The authors confirmed TIPS could be a treatment for recompensation of patients with cirrhosis according to Baveno VII. The paper identified age and post-TIPS portal pressure gradient as independent predictors of recompensation in patients with decompensated cirrhosis after TIPS. These results need to be validated in a larger prospective cohort.

Keywords: Cirrhosis recompensation; Transjugular intrahepatic portosystemic shunt; Portal pressure gradient; Predictor factor; Baveno VII

Core Tip: Approximately one-third of the patients experienced cirrhosis recompensation following transjugular intrahepatic portosystemic shunt (TIPS) and post-TIPS portal pressure gradient reduction below 12 mmHg contributes to the occurrence of recompensation. The selection of a smaller diameter (6 mm) stent may be an effective measure to reduce portal vein pressure while decreasing the incidence of postoperative hepatic encephalopathy.