Published online Mar 14, 2024. doi: 10.3748/wjg.v30.i10.1393
Peer-review started: December 24, 2023
First decision: January 4, 2024
Revised: January 16, 2024
Accepted: February 18, 2024
Article in press: February 18, 2024
Published online: March 14, 2024
Processing time: 81 Days and 8.7 Hours
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, affecting about 1/4th of the global population and causing a huge global economic burden. To date, no drugs have been approved for the treatment of NAFLD, making the correction of unhealthy lifestyles the principle method of treatment. Identifying patients with poor adherence to lifestyle correction and attempting to improve their adherence are therefore very important.
To develop and validate a scale that can rapidly assess the adherence of patients with NAFLD to lifestyle interventions.
The Exercise and Diet Adherence Scale (EDAS) was designed based on com
The EDAS consisted of 33 items in six dimensions, with a total of 165 points. Total EDAS score correlated significantly with daily number of exercise and daily reduction in calorie intake (P < 0.05 each), but not with overall weight loss. A total score of 116 was excellent in predicting adherence to daily reduction in calorie intake (> 500 kacl/d), (sensitivity/specificity was 100.0%/75.8%), while patients score below 97 could nearly rule out the possibility of daily exercise (sensitivity/specificity was 89.5%/44.4%). Total EDAS scores ≥ 116, 97-115, and < 97 points were indicative of good, average, and poor adherence, respectively, to diet and exercise recommendations.
The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.
Core Tip: This study developed and validated an Exercise and Diet Adherence Scale (EDAS) to rapidly assess adherence to lifestyle interventions in patients with non-alcoholic fatty liver disease (NAFLD). Patients can be grouped based on their EDAS scores and receive personalized treatments accordingly. The EDAS demonstrated reliability and effectiveness in predicting adherence to lifestyle changes and served as a vital tool in the clinical management of patients with NAFLD.