Letter to the Editor
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2023; 29(10): 1648-1650
Published online Mar 14, 2023. doi: 10.3748/wjg.v29.i10.1648
Reporting the cases of alcohol-associated hepatitis using the National Inpatient Sample data
Natalie Marlowe, Wei-Qi Lin, Suthat Liangpunsakul
Natalie Marlowe, Wei-Qi Lin, Durect Corporation, Cupertino, CA 95014, United States
Suthat Liangpunsakul, Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University, Indianapolis, IN 46202, United States
Author contributions: Marlowe N and Lin WQ drafted the manuscript; Liangpunsakul S criticized and edited the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Suthat Liangpunsakul, MD, Full Professor, Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University, 550 University Blvd, Indianapolis, IN 46202, United States. sliangpu@iu.edu
Received: October 25, 2022
Peer-review started: October 25, 2022
First decision: November 18, 2022
Revised: November 29, 2022
Accepted: March 2, 2023
Article in press: March 2, 2023
Published online: March 14, 2023
Processing time: 136 Days and 1.2 Hours
Abstract

The letter is to respond to the recent publication “Trends in hospitalization for alcoholic hepatitis from 2011 to 2017: A USA nationwide study” (World J Gastroenterol 2022; 28: 5036-5046). We noticed a significant difference in the total numbers of reported hospitalized alcohol-associated hepatitis (AH) patients between this publication and our publication on Alcohol Clin Exp Res (2022; 46: 1472-1481). We believe the number of “AH-related hospitalizations” inflated by the inclusion of patients with non-AH forms of alcohol-associated liver disease.

Keywords: Hospitalization; Alcoholic hepatitis; Alcohol-associated liver disease

Core Tip: We analyzed the most recent National Inpatient Sample data from 2015-2019 using International Classification of Diseases-10 codes and found an increase in alcohol-associated hepatitis (AH) cases from 110135 to 136620 in 2015 and 2019, respectively. The total numbers of reported AH patients in the retrospective study entitled “Trends in hospitalization for alcoholic hepatitis from 2011 to 2017: A USA nationwide study”, we believe, included patients with non-AH forms of alcohol-associated liver disease.