Published online Feb 28, 2022. doi: 10.3748/wjg.v28.i8.878
Peer-review started: September 13, 2021
First decision: November 7, 2021
Revised: November 10, 2021
Accepted: January 19, 2022
Article in press: January 19, 2022
Published online: February 28, 2022
Processing time: 163 Days and 15.8 Hours
Exercise-induced changes of the microbiome in inflammatory bowel diseases (IBD) is a promising field of research with the potential for personalized exercise regimes as a promising therapeutic adjunct for restoring gut dysbiosis and additionally for regulating immunometabolic pathways in the management of IBD patients. Structured exercise programmes in IBD patients of at least of 12 wk duration are more likely to result in disease-altering changes in the gut microbiome and to harness potential anti-inflammatory effects through these changes along with immunometabolic pathways.
Core Tip: Exercise-induced changes of the microbiome in inflammatory bowel diseases (IBD) is a promising field of research with the potential for personalized exercise regimes as a promising therapeutic adjunct for restoring gut dysbiosis and additionally for regulating immunometabolic pathways in the management of IBD patients. We have observed that exercise programmes of at least 12 wk duration are required to exert any meaningful effects on gut dysbiosis restoration and suggest that the positive effects of a more prolonged programme may extend to inflammatory mediation through regulation of immunometabolism.