Zheng QH, Hu J, Yi XY, Xiao XH, Zhou LN, Li B, Bo XT. Collagenous gastritis in a young Chinese woman: A case report. World J Gastroenterol 2022; 28(41): 5993-6001 [PMID: 36405104 DOI: 10.3748/wjg.v28.i41.5993]
Corresponding Author of This Article
Xiao-Tong Bo, MMed, Associate Chief Physician, Department of Gastroenterology, Affiliated Hospital of Guilin Medical University, No. 15 Lequn Road, Xiufeng District, Guilin 541001, Guangxi Province, China. b_xt@foxmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Nov 7, 2022; 28(41): 5993-6001 Published online Nov 7, 2022. doi: 10.3748/wjg.v28.i41.5993
Collagenous gastritis in a young Chinese woman: A case report
Qing-Hua Zheng, Jie Hu, Xiao-Yuan Yi, Xu-Hua Xiao, Li-Na Zhou, Bin Li, Xiao-Tong Bo
Qing-Hua Zheng, Jie Hu, Xiao-Yuan Yi, Xu-Hua Xiao, Li-Na Zhou, Bin Li, Xiao-Tong Bo, Department of Gastroenterology, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi Province, China
Author contributions: Zheng QH performed the Eesophagogastroduodenoscopy and endoscopic ultrasound, made the clinical diagnosis and treatment plan, and wrote the manuscript; Hu J performed the histopathological diagnosis; Yi XY collected the clinical data and performed the follow-up; Xiao XH completed the magnifying endoscopy; Zhou LN helped the endoscopists with the endoscopic procedures as a nurse; Li B supervised the diagnosis and treatment of this patient; Bo XT wrote the English version of the paper; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Tong Bo, MMed, Associate Chief Physician, Department of Gastroenterology, Affiliated Hospital of Guilin Medical University, No. 15 Lequn Road, Xiufeng District, Guilin 541001, Guangxi Province, China. b_xt@foxmail.com
Received: July 18, 2022 Peer-review started: July 18, 2022 First decision: September 8, 2022 Revised: September 21, 2022 Accepted: October 19, 2022 Article in press: October 19, 2022 Published online: November 7, 2022 Processing time: 108 Days and 12.2 Hours
Abstract
BACKGROUND
Collagenous gastritis (CG) is a rare condition whose pathogenesis may be related to immune abnormalities. We report a case of CG from China.
CASE SUMMARY
A 24-year-old woman presented with recurrent abdominal distension and discomfort for 3 mo. Upper gastrointestinal endoscopy found diffuse nodular elevation-depression changes in the mucosa of the entire gastric corpus. Endoscopic ultrasound showed predominant involvement of the lamina propria and submucosa, and computed tomography imaging showed mild enhancement of the gastric wall. Pathological histology revealed that the thickness of the subepithelial collagen band was about 40 μm, and the Masson trichrome staining result was positive and the Congo red staining result was negative. This case is consistent with the child-adolescent type of CG.
CONCLUSION
Serum pepsinogen I, pepsinogen II, pepsinogen I/II ratio, and gastrin-17 may be potential non-invasive monitoring markers. Currently, treatments for CG vary, and the likely prognosis is unknown. Individual cases of gastric cancer in patients with CG have been reported.
Core Tip: We report a case of collagenous gastritis. We introduce the clinical features, findings of esophagogastroduodenoscopy and endoscopic ultrasound, and response to treatment in this young female patient.
