Li Y, Liu WC, Chang B. Intestinal virome: An important research direction for alcoholic and nonalcoholic liver diseases. World J Gastroenterol 2022; 28(26): 3279-3281 [PMID: 36051333 DOI: 10.3748/wjg.v28.i26.3279]
Corresponding Author of This Article
Bing Chang, MD, Associate Professor, Department of Gastroenterology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110001, Liaoning Province, China. cb000216@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Jul 14, 2022; 28(26): 3279-3281 Published online Jul 14, 2022. doi: 10.3748/wjg.v28.i26.3279
Intestinal virome: An important research direction for alcoholic and nonalcoholic liver diseases
Yan Li, Wen-Cheng Liu, Bing Chang
Yan Li, Wen-Cheng Liu, Bing Chang, Department of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Author contributions: Li Y and Liu WC wrote this manuscript; Li Y and Chang B revised this manuscript; and all the authors contributed to the writing of this manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bing Chang, MD, Associate Professor, Department of Gastroenterology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping District, Shenyang 110001, Liaoning Province, China. cb000216@163.com
Received: November 3, 2021 Peer-review started: November 3, 2021 First decision: November 29, 2021 Revised: December 7, 2021 Accepted: June 13, 2022 Article in press: June 13, 2022 Published online: July 14, 2022 Processing time: 251 Days and 23.3 Hours
Abstract
In recent years, the interaction between the gut microflora and liver diseases has attracted much attention. The intestinal microflora is composed of bacteria, archaea, fungi and viruses. There are few studies on the intestinal virome, and whether it has a causal relationship with bacterial changes in the gut is still unclear. However, it is undeniable that the intestinal virome is also a very important portion of the blueprint for the development of liver diseases and the diagnosis and therapeutic modalities in the future.
Core Tip: As of the study of the gut microflora expands, the interaction between the intestinal virome and liver diseases has been gradually revealed. In this letter to the editor, we discuss the changes in the intestinal virome in patients with alcoholic liver disease and nonalcoholic liver disease, and provide suggestions for developing future diagnosis and treatment methods.
