Published online Apr 21, 2022. doi: 10.3748/wjg.v28.i15.1601
Peer-review started: June 2, 2021
First decision: June 22, 2021
Revised: July 2, 2021
Accepted: March 25, 2022
Article in press: March 25, 2022
Published online: April 21, 2022
Processing time: 316 Days and 13.5 Hours
Standard endoscopy with biopsy and narrow-band imaging with guided biopsy are techniques for the detection of Helicobacter pylori (H. pylori)-related gastritis and precancerous lesions. In this study, the authors compared standard endoscopy and magnified narrow-band imaging (commonly known as NBI-M) in the diagnosis of H. pylori infections, atrophic gastritis, and intestinal metaplasia. Although the sensitivity of NBI-M is better than standard endoscopy, the diagnostic accuracy did not differ substantially between the diagnostic modalities. Future prospective studies may guide endoscopists in difficult cases regarding which modality is more useful and cost-effective for the diagnosis of H. pylori-related gastritis and precancerous conditions.
Core Tip: Magnified narrow band imaging (NBI-M) is used for diagnosis of dysplastic and cancerous lesions. The study is the first of its kind to evaluate this modality for detection of Helicobacter pylori related gastritis and precancerous lesions. A procedure to be widely accepted should be cost effective and less time consuming. Whereas white light endoscopy is commonly used by endoscopist to detect any cancer or precancerous lesions, formal endoscopic training regarding use of NBI-M enhances feasibility and detection rate. Whether the combination of NBI-M and artificial intelligence can replace biopsy remains a million dollar question.