Kawaida H, Kono H, Hosomura N, Amemiya H, Itakura J, Fujii H, Ichikawa D. Surgical techniques and postoperative management to prevent postoperative pancreatic fistula after pancreatic surgery. World J Gastroenterol 2019; 25(28): 3722-3737 [PMID: 31391768 DOI: 10.3748/wjg.v25.i28.3722]
Corresponding Author of This Article
Hiromichi Kawaida, MD, PhD, Chief Doctor, Doctor, Surgeon, First Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuou-shi, Yamanashi 409-3898, Japan. kawaidah@yamanashi.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hiromichi Kawaida, Hiroshi Kono, Naohiro Hosomura, Hidetake Amemiya, Jun Itakura, Daisuke Ichikawa, First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan
Hideki Fujii, Department of Surgery, Kofu Manicipal Hospital, Yamanashi 400-0832, Japan
Author contributions: All authors contributed equally to this paper regarding the conception and design of the study, literature review and analysis, drafting and clinical revision and editing, and final approval of the final version.
Conflict-of-interest statement: No potential conflict of interest. No financial support.
Open-Access: This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hiromichi Kawaida, MD, PhD, Chief Doctor, Doctor, Surgeon, First Department of Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuou-shi, Yamanashi 409-3898, Japan. kawaidah@yamanashi.ac.jp
Telephone: +81-552-737390 Fax: +81-552-737390
Received: March 20, 2019 Peer-review started: March 20, 2019 First decision: June 10, 2019 Revised: June 20, 2019 Accepted: June 25, 2019 Article in press: June 26, 2019 Published online: July 28, 2019 Processing time: 131 Days and 7.7 Hours
Abstract
Postoperative pancreatic fistula (POPF) is one of the most severe complications after pancreatic surgeries. POPF develops as a consequence of pancreatic juice leakage from a surgically exfoliated surface and/or anastomotic stump, which sometimes cause intraperitoneal abscesses and subsequent lethal hemorrhage. In recent years, various surgical and perioperative attempts have been examined to reduce the incidence of POPF. We reviewed several well-designed studies addressing POPF-related factors, such as reconstruction methods, anastomotic techniques, stent usage, prophylactic intra-abdominal drainage, and somatostatin analogs, after pancreaticoduodenectomy and distal pancreatectomy, and we assessed the current status of POPF. In addition, we also discussed the current status of POPF in minimally invasive surgeries, laparoscopic surgeries, and robotic surgeries.
Core tip: We reviewed recent reports concerning postoperative pancreatic fistula (POPF)-related factors, such as reconstruction methods, anastomotic techniques, stent usage, prophylactic intra-abdominal drainage, and somatostatin analogs, after pancreaticoduodenectomy and distal pancreatectomy, and we assessed the current status of POPF.
