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Case Report
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 14, 2018; 24(6): 763-766
Published online Feb 14, 2018. doi: 10.3748/wjg.v24.i6.763
Gastroenteritis in an adult female revealing hemolytic uremic syndrome: Case report
Paulina Chinchilla-López, Vania Cruz-Ramón, Oscar Ramírez-Pérez, Nahum Méndez-Sánchez
Paulina Chinchilla-López, Vania Cruz-Ramón, Oscar Ramírez-Pérez, Nahum Méndez-Sánchez, Liver Research Unit, Medica Sur Clinic and Foundation, Mexico City 14050, Mexico
Author contributions: Chinchilla-Lopez P, Cruz-Ramón V and Ramirez-Pérez O analyzed the data and wrote the paper; Méndez-Sánchez N designed the report, diagnostic approach to patient with suspected gastroenteritis associated with hemolytic uremic Syndrome.
Informed consent statement: The patient involved in this study gave her written informed consent authorizing use and disclosure of her protected health information.
Conflict-of-interest statement: All authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nahum Méndez-Sánchez, MD, MSc, PhD, Professor, Liver Research Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, Col. Toriello Guerra, México City 14050, México. nmendez@medicasur.org.mx
Telephone: +525-55-4247200-4215 Fax: +525-55-6664031
Received: November 16, 2017
Peer-review started: November 17, 2017
First decision: December 13, 2017
Revised: December 15, 2017
Accepted: December 20, 2017
Article in press: December 20, 2017
Published online: February 14, 2018
Processing time: 81 Days and 4.2 Hours
Abstract

Nowadays acute gastroenteritis infection caused by Escherichia coli (E. coli) O157:H7 is frequently associated with hemolytic uremic syndrome (HUS), which usually developed after prodromal diarrhea that is often bloody. The abdominal pain accompanied by failure kidney is a suspicious symptom to develop this disorder. Their pathological characteristic is vascular damage which manifested as arteriolar and capillary thrombosis with abnormalities in the endothelium and vessel walls. The major etiological agent of HUS is enterohemorragic (E coli) strain belonging to serotype O157:H7. The lack of papers about HUS associated to gastroenteritis lead us to report this case for explain the symptoms that are uncommon. Furthermore, this report provides some strategies to suspect and make an early diagnosis, besides treatment approach to improving outcomes and prognosis for patients with this disorder.

Keywords: Gastroenteritis; Gastrointestinal hemorrhage; Hemolytic-uremic syndrome; Escherichia coli O157; Shiga-toxigenic Escherichia coli

Core tip: Bloody diarrhea and Hemolytic uremic syndrome are frequent caused by E. coli serotype O157:H7. The most causes of gastroenteritis are diagnosed as non-infectious illness and this could be the reason that clinicians did not usually associated with the hemolytic uremic syndrome development. This case report not only represents the importance of the diagnosis and the treatment approach, but also is one of the few studies where it is emphasized the gastrointestinal role and the critical symptoms that the clinical has to recognize it.