Mori H, Kobara H, Guan Y, Goda Y, Kobayashi N, Nishiyama N, Masaki T. Oval mucosal opening bloc biopsy after incision and widening by ring thread traction for submucosal tumor. World J Gastroenterol 2017; 23(39): 7185-7190 [PMID: 29093627 DOI: 10.3748/wjg.v23.i39.7185]
Corresponding Author of This Article
Hirohito Mori, MD, PhD, Doctor, Lecturer, Department of Gastroenterology and Neurology, Kagawa University, 1750-1 Ikenobe, Miki, Kita, Kagawa 761-0793, Japan. hiro4884@med.kagawa-u.ac.jp
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Hirohito Mori, Hideki Kobara, Yasuhiro Goda, Nobuya Kobayashi, Noriko Nishiyama, Tsutomu Masaki, Department of Gastroenterology and Neurology, Kagawa University, Kita, Kagawa 761-0793, Japan
Yu Guan, Departments of Pharmacology, Kagawa University, Kita, Kagawa 761-0793, Japan
Author contributions: Mori H was responsible for devising the research and writing the manuscript; Kobara H, Guan Y, Goda Y, Kobayashi N and Nishiyama N participated equally in the work; Masaki T provided a critical revision of the manuscript for intellectual content and was responsible for final approval of the manuscript.
Institutional review board statement: This study was approved by the ethics committees of Kagawa University Hospital (approval No. 51), and it is in accordance with the Declaration of Helsinki.
Informed consent statement: Patients were provided verbal and written informed consent.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest, and no corporate financing was received.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hirohito Mori, MD, PhD, Doctor, Lecturer, Department of Gastroenterology and Neurology, Kagawa University, 1750-1 Ikenobe, Miki, Kita, Kagawa 761-0793, Japan. hiro4884@med.kagawa-u.ac.jp
Telephone: +81-87-8912156 Fax: +81-87-8912158
Received: June 28, 2017 Peer-review started: June 28, 2017 First decision: July 25, 2017 Revised: August 15, 2017 Accepted: September 5, 2017 Article in press: September 5, 2017 Published online: October 21, 2017 Processing time: 115 Days and 23.5 Hours
Abstract
Gastric submucosal tumors (SMTs) less than 2 cm are generally considered benign neoplasms, and endoscopic observation is recommended, but SMTs over 2 cm, 40% of which are gastrointestinal stromal tumors (GISTs), have malignant potential. Although the Japanese Guidelines for GIST recommend partial surgical resection for GIST over 2 cm with malignant potential as well as en bloc large tissue sample to obtain appropriate and large specimens of SMTs, several reports have been published on tissue sampling of SMTs, such as with endoscopic ultrasound sound fine needle aspiration, submucosal tunneling bloc biopsy, and the combination of bite biopsy and endoscopic mucosal resection. Because a simpler, more accurate method is needed for appropriate treatment, we developed oval mucosal opening bloc biopsy after incision and widening by ring thread traction for submucosal tumor (OMOB) approach. OMOB was simple and enabled us to obtain large samples under direct procedure view as well as allowed us to restore to original mucosa.
Core tip: Gastric submucosal tumors (SMTs) less than 2 cm are generally considered benign neoplasms, and endoscopic observation is recommended, but SMTs over 2 cm, 40% of which are gastrointestinal stromal tumors (GISTs), have malignant potential. Although partial surgical resection for GIST over 2 cm with malignant potential as well as en bloc large tissue sample to obtain appropriate and large specimen of SMTs is recommended, several reports have been published on tissue sampling of SMTs. Because a simpler, more accurate method is needed for appropriate treatment, we developed oval mucosal opening bloc biopsy after incision and widening by ring thread traction approach.
