Li J, Zhang S, Zhou R, Zhang J, Li ZF. Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis. World J Gastroenterol 2017; 23(20): 3615-3623 [PMID: 28611514 DOI: 10.3748/wjg.v23.i20.3615]
Corresponding Author of This Article
Zong-Fang Li, MD, PhD, National Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University College of Medicine, 157 West 5th Road, Xi’an 710004, Shaanxi Province, China. lzf2568@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Li J, Zhang S, Zhou R, Zhang J, Li ZF. Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis. World J Gastroenterol 2017; 23(20): 3615-3623 [PMID: 28611514 DOI: 10.3748/wjg.v23.i20.3615]
World J Gastroenterol. May 28, 2017; 23(20): 3615-3623 Published online May 28, 2017. doi: 10.3748/wjg.v23.i20.3615
Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis
Jun Li, Shu Zhang, Rui Zhou, Jian Zhang, Zong-Fang Li
Jun Li, National Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, the Second Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an 710004, Shaanxi Province, China
Shu Zhang, Rui Zhou, Jian Zhang, Zong-Fang Li, National Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University College of Medicine, Xi’an 710004, Shaanxi Province, China
Author contributions: Li J and Zhang S collected the underlying material, wrote the initial draft of the manuscript; Li J, Zhang S, Zhou R, Zhang J and Li ZF designed the outline of the paper; Zhang S and Li ZF finalized and revised the manuscript; all authors have read and approved the final version of the manuscript.
Supported byNational Natural Science Foundation of China, No. 30171167, No. 30901945; Specialized Research Fund for the Doctoral Program of Higher Education, No. 20130201130009; Science and Technology Program of Shaanxi Province, No. 2012KTCQ03-15; and Science Research Foundation of the Second Affiliated Hospital of Xi’an Jiaotong University, No. YJ(QN)201311).
Conflict-of-interest statement: No potential conflicts of interest.
Correspondence to: Zong-Fang Li, MD, PhD, National Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, Department of General Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University College of Medicine, 157 West 5th Road, Xi’an 710004, Shaanxi Province, China. lzf2568@gmail.com
Telephone: +86-29-87678002 Fax: +86-29-87678634
Received: January 26, 2017 Peer-review started: February 2, 2017 First decision: February 23, 2017 Revised: March 13, 2017 Accepted: May 4, 2017 Article in press: May 4, 2017 Published online: May 28, 2017 Processing time: 120 Days and 9.6 Hours
Abstract
Acute pancreatitis (AP) is one of the most common diseases. AP is associated with significant morbidity and mortality, but it lacks specific and effective therapies. Traditional Chinese medicine (TCM) is one of the most popular complementary and alternative medicine modalities worldwide for the treatment of AP. The current evidence from basic research and clinical studies has shown that TCM has good therapeutic effects on AP. This review summarizes the widely used formulas, single herbs and monomers that are used to treat AP and the potential underlying mechanisms of TCM. Because of the abundance, low cost, and safety of TCM as well as its ability to target various aspects of the pathogenesis, TCM provides potential clinical benefits and a new avenue with tremendous potential for the future treatment of AP.
Core tip: Specific and effective therapies for the treatment of AP are lacking. Traditional Chinese medicine (TCM) exhibits beneficial, curative effects in basic research and clinical studies of AP treatment. Because of its abundance, low cost, safety and ability to target various aspects of AP pathogenesis, TCM provides a promising complementary and alternative therapy for the treatment of AP.
