Efficacy and safety of stellate ganglion block in chronic ulcerative colitis

doi:10.3748/wjg.v23.i17.3193

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Letter to the Editor

World J Gastroenterol. May 7, 2017; 23(17): 3193-3194
Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3193

Efficacy and safety of stellate ganglion block in chronic ulcerative colitis

Eugene Lipov, Ken Candido

Eugene Lipov, Ken Candido, Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, IL 60657, United States

Author contributions: Lipov E wrote the paper, analyzed data; Candido K revised the paper.

Conflict-of-interest statement: None to declare.

Correspondence to: Eugene Lipov, MD, Department of Anesthesiology, Advocate Illinois Masonic Medical Center, 3000 N Halsted St 700, Chicago, IL 60657, United States. elipovmd@aol.com

Telephone: +1-312-6180829 Fax: +1-312-6444343

Received: January 27, 2017
Peer-review started: February 4, 2017
First decision: March 16, 2017
Revised: April 10, 2017
Accepted: April 12, 2017
Article in press: April 12, 2017
Published online: May 7, 2017
Processing time: 99 Days and 18.7 Hours

Abstract

Sympathetic system modulation by stellate ganglion blockade may modulate immune dysfunction and significantly improve symptoms of chronic ulcerative colitis.

Keywords: Stellate ganglion block; Ulcerative colitis; Immune function; Chronic ulcerative colitis

Core tip: Utility of stellate ganglion block (SGB) seems to be expanding rapidly at this time, finding of its effect on ulcerative colitis is novel. Dr. Zhao’s explanation of the clinical observation seems to be increased blood flow. This theory may be refined based on prior reports of SGB having a significant immunologic effects. Since, ulcerative colitis is considered to be an auto immune disease, modulation immune system by SGB seems a more likely explanation. Further research of modulating immunologic system by utilizing sympathetic blocks may be spurred on by Dr. Zhao’s observation.