Luo LN, He LJ, Gao XY, Huang XX, Shan HB, Luo GY, Li Y, Lin SY, Wang GB, Zhang R, Xu GL, Li JJ. Evaluation of preoperative staging for esophageal squamous cell carcinoma. World J Gastroenterol 2016; 22(29): 6683-6689 [PMID: PMC4970469 DOI: 10.3748/wjg.v22.i29.6683]
Corresponding Author of This Article
Jian-Jun Li, MD, PhD, Associate Professor, Department of Endoscopy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute, Collaborative Innovation Center for Cancer Medicine, 651 Dong-Feng Road East, Guangzhou 510060, Guangdong Province, China. lijj@sysucc.org.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Lin-Na Luo, Long-Jun He, Xiao-Yan Gao, Xin-Xin Huang, Hong-Bo Shan, Guang-Yu Luo, Yin Li, Shi-Yong Lin, Guo-Bao Wang, Rong Zhang, Guo-Liang Xu, Jian-Jun Li, Department of Endoscopy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute, Collaborative Innovation Center for Cancer Medicine, Guangzhou 51006, Guangdong Province, China
Author contributions: Luo LN, He LJ and Gao XY contributed equally to this work; Luo LN, He LJ, Gao XY and Li JJ designed the study, drafted the paper, made critical revisions related to important intellectual content of the manuscript and gave final approval of the version of the article; Huang XX, Shan HB, Luo GY, Li Y, Lin SY, Wang GB, Zhang R and Xu GL contributed to critical revisions related to important intellectual content of the manuscript and final approval of the version of the article.
Conflict-of-interest statement: The authors have no conflicts of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jian-Jun Li, MD, PhD, Associate Professor, Department of Endoscopy, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute, Collaborative Innovation Center for Cancer Medicine, 651 Dong-Feng Road East, Guangzhou 510060, Guangdong Province, China. lijj@sysucc.org.cn
Telephone: +86-020-87343515 Fax: +86-020-87343515
Received: March 8, 2016 Peer-review started: March 9, 2016 First decision: April 14, 2016 Revised: April 29, 2016 Accepted: June 2, 2016 Article in press: June 2, 2016 Published online: August 7, 2016 Processing time: 142 Days and 22.5 Hours
Abstract
Esophageal squamous cell carcinoma (ESCC) is known for its rapid progression and poor outcomes. China has the highest incidence and mortality in the world. Diagnoses made at early stages and accurate staging are associated with better outcomes, all of which can play a significant role in the selection of treatment protocols. ESCC is staged according to the widely accepted TNM system. Common imaging modalities used in staging ESCC before treatment include endoscopy, computed tomography (CT), positron emission tomography (PET) and magnetic resonance imaging (MRI). Endoscopic ultrasound is useful for staging tumor depth and nodal status. Narrow band imaging is valuable for early stage disease assessment. CT and PET provide additional valuable information regarding node and metastasis staging. The ability of MRI to delineate ESCC is continuously being improved and adds information regarding locoregional status to routine examinations.
Core tip: Esophageal cancer is an aggressive malignant disease, as well as a growing health concern, with regard to mortality and prognosis. Esophageal squamous cell carcinoma is the prevailing histological type of esophageal cancer, with a high incidence in China. Staging of esophageal squamous cell carcinoma is based on the TNM system. Current imaging modalities include endoscopy, computed tomography, positron emission tomography and magnetic resonance imaging.
