Mondal U, Henkes N, Henkes D, Rosenkranz L. Cavernous hemangioma of adult pancreas: A case report and literature review. World J Gastroenterol 2015; 21(33): 9793-9802 [PMID: 26361427 DOI: 10.3748/wjg.v21.i33.9793]
Corresponding Author of This Article
Utpal Mondal, MD, Division of Gastroenterology and Nutrition, School of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States. mondalu@uthscsa.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Sep 7, 2015; 21(33): 9793-9802 Published online Sep 7, 2015. doi: 10.3748/wjg.v21.i33.9793
Cavernous hemangioma of adult pancreas: A case report and literature review
Utpal Mondal, Nichole Henkes, David Henkes, Laura Rosenkranz
Utpal Mondal, Laura Rosenkranz, Division of Gastroenterology and Nutrition, School of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Nichole Henkes, David Henkes, Department of Pathology and Laboratory, CHRISTUS Santa Rosa Hospital, San Antonio, TX 78240, United States
Author contributions: Mondal U designed the paper, did the acquisition, analysis and interpretation of data, reviewed literature and wrote the paper; Henkes N did literature search and proof reading; Henkes D was responsible for cytopathology and pathology; and Rosenkranz L provided clinical care including endoscopy and made critical revision of the manuscript; all authors approved the final version.
Institutional review board statement: The case study was reviewed and approved by the Office of the Institutional Review Board of the UT Health Science Center San Antonio.
Informed consent statement: Patient provided informed written consent for this publication.
Conflict-of-interest statement: None of the authors has any disclosure to make.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Utpal Mondal, MD, Division of Gastroenterology and Nutrition, School of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States. mondalu@uthscsa.edu
Telephone: +1-210-5674880 Fax: +1-210-5671976
Received: April 5, 2015 Peer-review started: April 7, 2015 First decision: April 23, 2015 Revised: May 29, 2015 Accepted: June 26, 2015 Article in press: June 26, 2015 Published online: September 7, 2015 Processing time: 155 Days and 7.8 Hours
Abstract
Pancreatic hemangioma is a rare type of benign vascular tumor. Low clinical suspicion and inability of current cross sectional imaging techniques to differentiate it from other pancreatic lesions, contribute to the difficulty in making the correct diagnosis. Without a definitive diagnosis, and due to concern for malignancy, in many instances, surgery is performed. We report a case of pancreas cavernous hemangioma in an 18-year-old female. The patient presented with three-month history of epigastric pain. Physical examination and routine blood tests were normal. Abdominal Computed Tomography scan revealed a 5 cm × 6 cm complex non-enhancing cystic mass in the head of pancreas. Magnetic resonance imaging, endoscopic ultrasonography (EUS) and EUS guided fine needle aspiration cytology were non-diagnostic. Because of uncontrolled symptoms, the patient underwent surgical resection. Histopathology and Immunohistochemical staining confirmed the diagnosis of cavernous hemangioma of pancreas.
Core tip: Pancreas hemangioma is a very rare pathological finding in adulthood. It may mimic other more common pancreatic lesions. Diagnosis is difficult, due to its rarity, and the absence of typical radiological findings of hemangioma. It should be considered in the differential diagnosis of cystic, mixed and solid pancreatic lesions. Surgical resection is the effective treatment in symptomatic cases, while providing a final diagnosis, however, surgery may not be necessary at all.
