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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 28, 2015; 21(32): 9503-9511
Published online Aug 28, 2015. doi: 10.3748/wjg.v21.i32.9503
Endoscopic treatments for small gastric subepithelial tumors originating from muscularis propria layer
Yu Zhang, Li-Ping Ye, Xin-Li Mao
Yu Zhang, Li-Ping Ye, Xin-Li Mao, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical College, Linhai 317000, Zhejiang Province, China
Author contributions: Zhang Y and Ye LP contributed equally to this paper; Zhang Y, Ye LP and Mao XL designed and performed the research; Zhang Y drafted the manuscript; Ye LP provided final approval of this article; and Mao XL analyzed the data.
Supported by Project of the Zhejiang Province Bureau of Health, No. 2013KYA226 and No. 2013KYA229; and Taizhou City Science and Technology Bureau (121ky08).
Conflict-of-interest statement: The authors declared that they have no conflicts of interest to this study.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Li-Ping Ye, Department of Gastroenterology, Taizhou Hospital of Zhejiang Province, Wenzhou Medical College, 150 Ximen Street, Linhai 317000, Zhejiang Province, China. xmcx783@126.com
Telephone: +86-576-85199171 Fax: +86-576-85199171
Received: February 10, 2015
Peer-review started: February 11, 2015
First decision: March 10, 2015
Revised: April 15, 2015
Accepted: July 8, 2015
Article in press: July 8, 2015
Published online: August 28, 2015
Processing time: 199 Days and 6.7 Hours
Abstract

Minimally invasive endoscopic resection has become an increasingly popular method for patients with small (less than 3.5 cm in diameter) gastric subepithelial tumors (SETs) originating from the muscularis propria (MP) layer. Currently, the main endoscopic therapies for patients with such tumors are endoscopic muscularis excavation, endoscopic full-thickness resection, and submucosal tunneling endoscopic resection. Although these endoscopic techniques can be used for complete resection of the tumor and provide an accurate pathological diagnosis, these techniques have been associated with several negative events, such as incomplete resection, perforation, and bleeding. This review provides detailed information on the technical details, likely treatment outcomes, and complications associated with each endoscopic method for treating/removing small gastric SETs that originate from the MP layer.

Keywords: Gastric subepithelial tumors; Endoscopic treatment; Submucosal tunneling endoscopic resection; Endoscopic muscularis excavation; Endoscopic full-thickness resection

Core tip: Minimally invasive endoscopic resection has become an increasingly popular method for small gastric subepithelial tumors (SETs) that originate from the muscularis propria (MP) layer. Currently, the main endoscopic therapies for patients with such tumors are endoscopic muscularis excavation, endoscopic full-thickness resection, and submucosal tunneling endoscopic resection. This review provides detailed information on the technical details, likely treatment outcomes, and complications associated with each endoscopic method for treating small gastric SETs that originate from the MP layer.