Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 21, 2015; 21(11): 3435-3440
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3435
Gastrointestinal hemorrhage due to ileal metastasis from primary lung cancer
Wei Liu, Wei Zhou, Wei-Lin Qi, Ya-Dan Ma, Yun-Yun Xu
Wei Liu, Wei Zhou, Wei-Lin Qi, Ya-Dan Ma, Yun-Yun Xu, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Author contributions: Zhou W and Liu W performed the operation; Qi WL, Ma YD and Xu YY collected case data and prepared the photos; Liu W wrote the manuscript; Zhou W proofread and revised the manuscript; all authors approved the final version to be published.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Wei Zhou, MD, Department of General Surgery, Sir Run Run Shaw Hospital, No. 3 East Qingchun Road, Hangzhou 310016, China. nuzwlvran@aliyun.com
Telephone: +86- 571-86090073 Fax: +86- 571-86090073
Received: July 24, 2014
Peer-review started: July 25, 2014
First decision: August 15, 2014
Revised: September 21, 2014
Accepted: November 11, 2014
Article in press: November 11, 2014
Published online: March 21, 2015
Processing time: 238 Days and 0.6 Hours
Abstract

We report a patient with small intestinal metastasis from lung squamous cell carcinoma. A 66-year-old man who underwent radical lung cancer surgery was admitted to our hospital. Before starting his fifth cycle of chemotherapy, he was found to have a positive fecal occult blood test. Abdominal computed tomography scan revealed an ileal tumor with mesenteric lymph node enlargement. He underwent laparoscopic resection of the involved small intestine and mesentery. Histopathological analysis confirmed metastasis from lung cancer. We conducted a review of the literature and 64 documented cases of small intestinal metastasis from lung cancer were found. The pathologic diagnosis, clinical presentation, site of metastasis, and survival time in these cases were reviewed.

Keywords: Lung cancer; Metastasis; Gastrointestinal hemorrhage; Gastrointestinal neoplasms; Small intestine

Core tip: Gastrointestinal tract metastases from lung cancer are relatively rare. We describe a patient with melena due to small intestinal metastasis from lung squamous cell carcinoma. We collected 64 similar documented cases from 2000 to date, and reviewed the pathologic diagnosis, clinical presentation, site of metastasis, treatment, and survival time.