Case Report
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World J Gastroenterol. Oct 7, 2014; 20(37): 13632-13636
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13632
Long-term survival after enucleation of a giant esophageal gastrointestinal stromal tumor
Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye
Zhi-Min Mu, Yuan-Cai Xie, Xu-Xing Peng, Hai Zhang, Gang Hui, Hao Wu, Ji-Xian Liu, Bao-Kun Chen, Da Wu, Yi-Wang Ye, Department of thoracic surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China
Author contributions: Mu ZM and Ye YW contributed to the manuscript writing and revision; Mu ZM, Xie YC and Peng XX did the surgery; all authors gave their approval in publishing this version of the manuscript.
Correspondence to: Yi-Wang Ye, Attending Physician, Department of thoracic surgery, Peking University Shenzhen Hospital, Lianhua Road N0.1120, Shenzhen 518036, Guangdong Province, China. yyw.ghl@163.com
Telephone: +86-20-83923333 Fax: +86-20-83923333
Received: November 8, 2013
Revised: March 16, 2014
Accepted: June 20, 2014
Published online: October 7, 2014
Processing time: 332 Days and 19.7 Hours
Abstract

Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract. Less than 1% occurs in the esophagus. Surgery is the primary treatment for patients with GISTs. We report a 29-year-old male was admitted after the detection of a posterior mediastinal mass during work-up with routine examination. He did not have any disease-related symptoms. The physical examination was unremarkable. Chest computed tomographic scan, the barium esophagogram and endoscopic esophageal ultrasound showed benign neoplasm. The patient was performed an enucleation surgery through the right posterolateral thoracotomy. The pathology revealed a 13.0 cm × 12.0 cm × 5.0 cm mass. The tumor was CD117 (C-kit), PDGFRA and DOG1 positive. These findings were consistent with a GIST of the esophagus. So the diagnosis of GIST of esophagus was confirmed. The pathological diagnosis of low grade of GIST of esophagus was confirmed. The patient has no evidence of recurrence and is in good clinical conditions up-to date, five years after surgery.

Keywords: Esophageal gastrointestinal stromal tumor; Long-term survival; Enucleation; Surgery; Follow-up

Core tip: We report a case of giant esophageal gastrointestinal stromal tumor in a 29-year-old male successfully treated with enucleation. The patient has no evidence of recurrence and is in good clinical conditions up-to date, five years after surgery.