Prospective Study
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World J Gastroenterol. Oct 7, 2014; 20(37): 13591-13598
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13591
Gastric emptying evaluation by ultrasound prior colonoscopy: An easy tool following bowel preparation
Romain Coriat, Vanessa Polin, Ammar Oudjit, Franck Henri, Marion Dhooge, Sarah Leblanc, Chantal Delchambre, Anouk Esch, Tessa Tabouret, Maximilien Barret, Frédéric Prat, Stanislas Chaussade
Romain Coriat, Vanessa Polin, Marion Dhooge, Sarah Leblanc, Anouk Esch, Tessa Tabouret, Maximilien Barret, Frédéric Prat, Stanislas Chaussade, Gastroenterology unit and endoscopy unit, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), 75014 Paris, France
Ammar Oudjit, Radiology Department, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), 75014 Paris, France
Franck Henri, Chantal Delchambre, Laboratoires Mayoly Spindler, 78401 Chatou Cedex, France
Author contributions: Coriat R, Polin V, Henri F and Chaussade S designed research; Coriat R, Polin V, Henri F, Dhooge M, Leblanc S, Delchambre C, Esch A, Tabouret T, Barret M, Prat F and Chaussade S performed research; Coriat R and Polin V contributed analytic tools; Polin V, Coriat R, Oudjit A and Chaussade S analyzed data; and Coriat R, Polin V, Oudjit A Henri F and Chaussade S wrote the paper.
Correspondence to: Romain Coriat, MD, PhD, Gastroenterology unit and endoscopy unit, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Pavillon Achard, 27 rue du faubourg St Jacques, 75014 Paris, France. romain.coriat@cch.aphp.fr
Telephone: +33-1-58411952 Fax: +33-1-79734881
Received: February 13, 2014
Revised: March 23, 2014
Accepted: May 29, 2014
Published online: October 7, 2014
Processing time: 236 Days and 15.7 Hours
Abstract

AIM: To investigate the gastric emptying after bowel preparation to allow general anaesthesia.

METHODS: A prospective, non-comparative, and non-randomized trial was performed and registered on Eudra CT database (2011-002953-80) and on www.trial.gov (NCT01398098). All patients had a validated indication for colonoscopy and a preparation using sodium phosphate (NaP) tablets. The day of the procedure, patients took 4 tablets with 250 mL of water every 15 min, three times. The gastric volume was estimated every 15 min from computed antral surfaces and weight according to the formula of Perlas et al (Anesthesiology, 2009). Colonoscopy was performed within the 6 h following the last intake.

RESULTS: Thirty patients were prospectively included in the study from November 2011 to May 2012. The maximum volume of the antrum was 212 mL, achieved 15 min after the last intake. 24%, 67% and 92% of subjects had an antral volume below 20 mL at 60, 120 and 150 min, respectively. 81% of patients had a Boston score equal to 2 or 3 in each colonic segment. No adverse events leading to treatment discontinuation were reported.

CONCLUSION: Gastric volume evaluation appeared to be a simple and reliable method for the assessment of gastric emptying. Data allow considering the NaP tablets bowel preparation in the morning of the procedure and confirming that gastric emptying is achieved after two hours, allowing general anaesthesia.

Keywords: Colonoscopy; Preparation; Ultrasound; Gastric emptying

Core tip: Gastric emptying have never been evaluate prior colonoscopy. An evaluation by ultrasound prior colonoscopy appeared has an easy tool to identify complete gastric emptying and will allow anesthesiologist to perform sedation.