Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.74
Revised: January 31, 1996
Accepted: March 1, 1996
Published online: September 15, 1996
AIM: To study the relationship between fasting plasma motilin gastrointestinal electric activity and gastrointestinal motility.
METHODS: The 45 cases of chronic gastritis were diagnosed by gastroscopy. Fasting plasma motilin (normal 326 ± 58 ng/L) were determined by radioimmunoassay (RIA) and fasting electrogastrointestinagram were recorded.
RESULTS: The level of plasma motilin in 45 cases of chronic gastritis was 24.55-539.51 ng/L. Average was 201.81 ± 100.86 ng/L. The level of plasma motilin of 7 cases (15.56%) was normal, in 36 cases (80%) it was obvious low, and in 2 cases (4.44%) it was high. The frequency of electrogastrogram of 16 cases (35.56%) was normal. In them, 12 cases (26.67%) had bradygastria, 7 cases (15.56%) had tachygastria and 10 cases (22.22%) had arrhythmia. Amplitude and average area of electrogastrointestinogram were lower than normal.
CONCLUSION: The changes of clinical symptoms, fasting plasma motilin and electrogastrointestinogram are correspondent to each other. The motilin concordant with function of gastrointestinal motility. Intensity of gastrointestinal electric activity is directly affected by concentration of motilin.