Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.200
Revised: January 21, 1996
Accepted: June 9, 1996
Published online: September 15, 1996
AIM: In order to explain improvement of dyspeptic symptoms in patients with proximal gastrectomy, the gastric emptying, electrogastrography (EGG) and effect of cisapride were studied in 16 cases with radiopaque markers.
RESULTS: The findings showed that the early post operation gastric emptying in patients was the same as that in controls, but later post operation gastric emptying was significantly delayed (P < 0.01). It is suggested that the loss of fundus storage function and the decrease of gastric peristalsis after proximal gastrectomy may affect the gastric emptying. EGG showed that 13 cases (81.2%) were gastric dysrhythmias. Further studies showed that there was no one to one correlation between the EGG and gastric emptying. A normal EGG recording may not guarantee normal gastric emptying. We found that cisapride significantly increased the rate of gastric emptying (P < 0.05) but did not reach the normal levels, and improved the gastric dysrhythmias and dyspeptic symptom in a great number of patients with proximal gastrectomy.