Published online Dec 15, 1996. doi: 10.3748/wjg.v2.i4.197
Revised: July 21, 1996
Accepted: September 15, 1996
Published online: December 15, 1996
AIM: To investigate the changes of small intestinal migrating myoelectric complex (MMC) and regulatory effect of Jiawei Sijunzi Decoction in 8.0 Gy irradiated rats.
METHODS: The MMC of the intestine of rats was recorded using chronically implanted electrodes at different parts of the small intestine to analyse duration of four phases of MMC and its cycle before and after irradiation and to investigate the regulatory effect of Jiawei Sijunzi Decoction.
RESULTS: From 1 h to 7 d after 8.0 Gy irradiation the MMC cycle in most of rats disappeared and only phase II existed with minute’s rhythm. From 1 h to 3 d after irradiation, the MMC cycle appeared in a few rats with the duration of phase II shortened significantly (P < 0.05). Results of observation on effects of Jiawei Sijunzi Decoction on MMC after irradiation showed that the changes in phase and cycle of MMC were normalized basically by medication.
CONCLUSION: Jiawei Sijunzi Decoction can improve the intestinal disturbances caused by radiation, and this might be one of the reasons for its alleviating effect on radiation induced diarrhea.