Clinical Articles
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(3): 158-160
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.i3.158
Comparative study on the effects of hepatic arterial embolization with Bletilla striata or Gelfoam in treatment of primary hepatic carcinoma
Gan-Sheng Feng, B Kramann, Chuan-Sheng Zheng, Ru-Ming Zhou, Bo Liang, Yan-Fang Zhang
Gan-Sheng Feng, B Kramann, Chuan-Sheng Zheng, Ru-Ming Zhou, Bo Liang, Yan-Fang Zhang, Department of Radiology; Union Hospital of Tongji Medical University, Wuhan 430022, China
Gan-Sheng Feng, Professor of Radiology, Director of the Department of Radiology. Has previously published 36 papers and six books.
Author contributions: All authors contributed equally to the work.
Supported by the National Natural Science Foundation of China, No. 93019512.
Correspondence to: Dr. Gan-Sheng Feng, Professor, Department of Radiology, Union Hospital of Tongji Medical University, Wuhan 430022, China
Telephone: +86-27-5807711-598
Received: July 19, 1996
Revised: August 6, 1996
Accepted: August 27, 1996
Published online: September 15, 1996
Abstract

AIM: To study the safety and efficacy of hepatic arterial embolization (HAE) with Bletilla striata powders containing traditional Chinese herbs in the treatment of primary hepatic carcinoma (PHC).

METHODS: From May 1990 to September 1993, 106 patients with PHC were treated by HAE with different types of Bletilla striata powders (n = 56) or Gelfoam powders (n = 50) under clearly specified conditions. We analyzed the effects and complications associated with these two types of treatment.

RESULTS: The Bletilla striata powders produced extensive and permanent proximal embolization of the hepatic artery, and stimulated the formation of collateral circulation. Treatment could be stopped for as long as 6-12 mo, and there was obvious evidence of tumor necrosis and shrinkage. The patient survival rates at 1, 2, and 3 years were 81.9%, 44.9%, and 33.6%, respectively, and the mean survival time without a serious complication was 19.8 mo. Patients in the Bletilla striata group displayed better clinical effects from their treatment when compared with patients in the Gelfoam group.

CONCLUSION: Bletilla striata powders are superior to Gelfoam powders when used for angioembolus in patients with hepatic carcinoma.

Keywords: Liver neoplasms/therapy; Embolization; Therapeutic Bletilla striata