Published online Nov 7, 2013. doi: 10.3748/wjg.v19.i41.7205
Revised: July 21, 2013
Accepted: August 12, 2013
Published online: November 7, 2013
Processing time: 189 Days and 7.1 Hours
Intramural duodenal hematoma is a rare cause of a proximal gastrointestinal tract obstruction. Presentation of intramural duodenal hematoma most often occurs following blunt abdominal trauma in children, but spontaneous non-traumatic cases have been linked to anticoagulant therapy, pancreatitis, malignancy, vasculitis and endoscopy. We report an unusual case of spontaneous intramural duodenal hematoma presenting as an intestinal obstruction associated with acute pancreatitis in a patient with established von Willebrand disease, type 2B. The patient presented with abrupt onset of abdominal pain, nausea, and vomiting. Computed tomography imaging identified an intramural duodenal mass consistent with blood measuring 4.7 cm × 8.7 cm in the second portion of the duodenum abutting on the head of the pancreas. Serum lipase was 3828 units/L. Patient was managed conservatively with bowel rest, continuous nasogastric decompression, total parenteral nutrition, recombinant factor VIII (humateP) and transfusion. Symptoms resolved over the course of the hospitalization. This case highlights an important complication of an inherited coagulopathy.
Core tip: Spontaneous non-traumatic duodenal hematoma has been linked to coagulopathy, but this case includes a rare form of coagulopathy in von Willebrand type 2B. Early identification with computed tomography imaging and treatment of the coagulopathy aided the usage of conservative therapy which allowed the patient to avoid surgical intervention consistent with prior successful cases of duodenal hematomas.