Letters To The Editor
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World J Gastroenterol. Jun 21, 2013; 19(23): 3711-3712
Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3711
Response to Abadi and Kusters, World J Gastroenterol 19: 429-430
Alireza Rafiei, Jeremy J Gilbreath, D Scott Merrell
Alireza Rafiei, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari 48471-91971, Iran
Jeremy J Gilbreath, D Scott Merrell, Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States
Author contributions: Rafiei A, Gibreath JJ, and Merrell DS wrote this letter.
Correspondence to: Alireza Rafiei, PhD, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Khazar Sq, KM18 Khazarabad Road, Sari 48471-91971, Iran. rafiei1710@gmail.com
Telephone: +98-151-3543614 Fax: +98-151-3261244
Received: March 15, 2013
Revised: April 16, 2013
Accepted: May 16, 2013
Published online: June 21, 2013
Processing time: 96 Days and 18.2 Hours
Abstract

In a recent study, Rafiei et al, reported a link between a C150T polymorphism in the human inducible nitric oxide gene and Helicobacter pylori infection as a risk factor for gastric cancer among an Iranian population. Subsequently, Abadi and Kusters published a letter to the editor questioning the validity of the study because of a supposed flaw in primer design. Here we respond to the claims of Abadi and Kusters and show that the results reported in the original article are valid.

Keywords: Inducible nitric oxide synthetase; Helicobacter pylori; Gastric cancer

Core tip: In a recent Letter to the Editor, Abadi and Kusters brought into question the validity of a study published by Rafiei et al. Herein we respond to the claims made by Abadi and Kusters, and show that the results reported in the article originally published by Rafiei et al, are valid.