Xu GQ, Chen HT, Xu CF, Teng XD. Esophageal granular cell tumors: Report of 9 cases and a literature review. World J Gastroenterol 2012; 18(47): 7118-7121 [PMID: 23323018 DOI: 10.3748/wjg.v18.i47.7118]
Corresponding Author of This Article
Guo-Qiang Xu, MD, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China. zyxgq@sina.cn
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Dec 21, 2012; 18(47): 7118-7121 Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.7118
Esophageal granular cell tumors: Report of 9 cases and a literature review
Guo-Qiang Xu, Hong-Tan Chen, Cheng-Fu Xu, Xiao-Dong Teng
Guo-Qiang Xu, Hong-Tan Chen, Cheng-Fu Xu, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Xiao-Dong Teng, Department of Pathology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Xu GQ designed the research; Xu GQ, Chen HT, Xu CF and Teng XD performed the research; Xu GQ analyzed the data; Chen HT and Xu CF wrote the paper.
Correspondence to: Guo-Qiang Xu, MD, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China. zyxgq@sina.cn
Telephone: +86-571-87236518 Fax: +86-571-87236611
Received: July 10, 2012 Revised: October 13, 2012 Accepted: October 30, 2012 Published online: December 21, 2012
Abstract
Esophageal granular cell tumors (GCTs) are rare tumors of the esophagus. We evaluated the clinical and pathologic features of 9 esophageal GCT patients (5 men and 4 women) from our institute and reviewed the related disease literature. Patient age ranged from 25 to 53 years (mean: 41 years). All the patients were asymptomatic or presented with non-specific symptoms. Most GCTs occurred in the distal esophagus and were less than 6 mm in diameter. Computational analysis showed that the average gray-scale endoscopic ultrasound images of esophageal GCTs were greater than that of esophageal leiomyomas. Eight patients were treated by endoscopic resection, and 1 patient underwent surgical excision. No post-therapy recurrence or metastasis developed during follow-up (mean: 36.4 mo, range: 1-72 mo).