Brief Article
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World J Gastroenterol. Aug 21, 2012; 18(31): 4169-4174
Published online Aug 21, 2012. doi: 10.3748/wjg.v18.i31.4169
Sensitivity of the suspected blood indicator: An experimental study
Sung Chul Park, Hoon Jai Chun, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hong Sik Lee, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu
Sung Chul Park, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 200-722, South Korea
Hoon Jai Chun, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yong Sik Kim, Yoon Tae Jeen, Hong Sik Lee, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul 136-705, South Korea
Author contributions: Park SC, Chun HJ, Kim ES, and Keum B performed the research; Seo YS, Kim YS, Jeen YT, Lee HS, Um SH, Kim CD, and Ryu HS analyzed the data; and Park SC and Chun HJ wrote the article.
Correspondence to: Hoon Jai Chun, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, 126-1, Anam-dong 5-ga, Seongbuk-gu, Seoul 136-705, South Korea. drchunhj@chol.com
Telephone: +82-2-9206555 Fax: +82-2-9531943
Received: February 11, 2012
Revised: May 2, 2012
Accepted: May 5, 2012
Published online: August 21, 2012
Abstract

AIM: To investigate whether suspected blood indicator (SBI) in capsule endoscopy (CE) is affected by background color and capsule passage velocity.

METHODS: Experimental models of the small intestine constructed from paper in a variety of colors were used to simulate the background colors observed in CE images. The background colors studied included very pale yellow, yellow, very pale magenta, light grayish pink, burnt sienna, and deep and dark brown, and red spots were attached inside them. An endoscopic capsule was manually passed through the models. The rate of detection of the red spots by the SBI was evaluated based on the colors of the models and the capsule passage velocities (0.5 cm/s, 1 cm/s, and 2 cm/s).

RESULTS: The rate of detection of the red spots by the SBI differed significantly according to the background color of the model (P < 0.001). Detection rates were highest for backgrounds of very pale magenta, burnt sienna, and yellow, in that order. They were lowest for backgrounds of dark brown and very pale yellow. The rate of detection of red spots by the SBI tended to decrease at rapid capsule passage velocities (1-2 cm/s) compared to slow velocities (0.5 cm/s) for backgrounds of very pale yellow (P = 0.042), yellow (P = 0.001), very pale magenta (P = 0.002), and burnt sienna (P = 0.001). No significant differences in the rate of detection were observed according to velocity for light grayish pink (P = 0.643) or dark brown (P = 0.396).

CONCLUSION: SBI sensitivity was affected by background color and capsule passage velocity in the models. These findings may facilitate the rapid detection of bleeding lesions by CE.

Keywords: Capsule endoscopy; Suspected blood indicator; Sensitivity; Background color; Passage velocity