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World J Gastroenterol. Dec 7, 2011; 17(45): 4945-4951
Published online Dec 7, 2011. doi: 10.3748/wjg.v17.i45.4945
Health-related quality of life outcomes after cholecystectomy
Amedeo Carraro, Dania El Mazloum, Florian Bihl
Amedeo Carraro, Department of Surgery, Veneto Oncological Institute, IRCCS, 35128 Padova, Italy
Dania El Mazloum, School of Medicine, University of Padova, 35128 Padova, Italy
Florian Bihl, Gastroenterology and Hepatology Unit, San Giovanni Hospital, 6500 Bellinzona, Switzerland
Florian Bihl, Gastroenterology and Hepatology Service, University Hospital of Geneva, 1201 Geneva, Switzerland
Author contributions: Bihl F, Carraro A and El Mazloum D designed the study; Carraro A and El Mazloum D performed the research; Bihl F and Carraro A contributed analytic tools; Bihl F, Carraro A and El Mazloum D analyzed the data and wrote the paper; all authors revised and approved the final version of the manuscript.
Correspondence to: Florian Bihl, MD, Gastroenterology and Hepatology Unit, San Giovanni Hospital, Via Ospedale 32, 6500 Bellinzona, Switzerland. florian.bihl@eoc.ch
Telephone: +41-91-8118708 Fax: +41-91-8118708
Received: December 23, 2010
Revised: June 15, 2011
Accepted: June 22, 2011
Published online: December 7, 2011
Abstract

Gallbladder diseases are very common in developed countries. Complicated gallstone disease represents the most frequent of biliary disorders for which surgery is regularly advocated. As regards, cholecystectomy represents a common abdominal surgical intervention; it can be performed as either an elective intervention or emergency surgery, in the case of gangrene, perforation, peritonitis or sepsis. Nowadays, the laparoscopic approach is preferred over open laparotomy. Globally, numerous cholecystectomies are performed daily; however, little evidence exists regarding assessment of post-surgical quality of life (QOL) following these interventions. To assess post-cholecystectomy QOL, in fact, documentation of high quality care has been subject to extended discussions, and the use of patient-reported outcome satisfaction for quality improvement has been advocated for several years. However, there has been little research published regarding QOL outcomes following cholecystectomy; in addition, much of the current literature lacks systematic data on patient-centered outcomes. Then, although several tools have been used to measure QOL after cholecystectomy, difficulty remains in selecting meaningful parameters in order to obtain reproducible data to reflect postoperative QOL. The aim of this study was to review the impact of surgery for gallbladder diseases on QOL. This review includes Medline searches of current literature on QOL following cholecystectomy. Most studies demonstrated that symptomatic patients profited more from surgery than patients receiving an elective intervention. Thus, the gain in QOL depends on the general conditions before surgery, and patients without symptoms profit less or may even have a reduction in QOL.

Keywords: Gallbladder disease; Gallstones; Quality of life; Laparoscopy