Brief Article
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World J Gastroenterol. Sep 7, 2010; 16(33): 4206-4209
Published online Sep 7, 2010. doi: 10.3748/wjg.v16.i33.4206
A newly designed big cup nitinol stent for gastric outlet obstruction
Ding Shi, Sheng-Hui Liao, Jian-Ping Geng
Ding Shi, Department of Gastroenterology, the First People’s Hospital of Yuhang District, Hangzhou 311100, Zhejiang Province, China
Sheng-Hui Liao, School of Information Science and Engineering Central South University, Changsha 410083, Hunan Province, China
Jian-Ping Geng, Institute for Biomedical Engineering, Nanjing University of Technology, Nanjing 210009, Jiangsu Province, China
Author contributions: Shi D made substantial contributions to the conception of the study and clinical work; Liao SH designed the medical tool; Geng JP contributed to the study design, acquisition and analysis of data, and paper revision.
Correspondence to: Jian-Ping Geng, PhD, Institute for Biomedical Engineering, Nanjing University of Technology, PO Box 128, 5 Xinmofan Road, Nanjing 210009, Jiangsu Province, China. jpgeng2005@163.com
Telephone: +86-25-83172262 Fax: +86-25-83172212
Received: May 7, 2010
Revised: June 3, 2010
Accepted: June 10, 2010
Published online: September 7, 2010
Abstract

AIM: To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer.

METHODS: The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in diameter) covered by a polyethylene membrane and a distal sphericity (20 mm in length and 28 mm in diameter). Half of the proximal big cup segment is also covered by a polyethlene membrane, which is adjacent to the middle part of the stent. The stent is preloaded in a 6.0-mm-diameter introducer system. Thirteen patients with gastric outlet obstruction resulting from gastric cancer received the new stents under endoscopic and fluoroscopic guidance.

RESULTS: Technical success was achieved in 12 of 13 (92.3%) patients. Among the 12 patients in whom endoscopic stent was placed successfully, the clinical success rate was 91.7% during a follow-up of average 6.5 mo. During the first month follow-up, the migration rate was 0%, recurrent obstruction 0% and gastric bleeding 8.3%. During the follow-up between 2-12 mo, no migration, recurrent obstruction and gastric bleeding occurred.

CONCLUSION: The proximal big cup segment seems to be effective and promising for technical efficacy, clinical outcome, and preventing migration and tumor ingrowth and increasing the emptying rate of sinus ventriculi.

Keywords: Endoscopic; Gastric outlet; Stenosis; Obstruction; Stents