Brief Article
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World J Gastroenterol. Sep 7, 2010; 16(33): 4164-4168
Published online Sep 7, 2010. doi: 10.3748/wjg.v16.i33.4164
Outcome of surgical treatment of intestinal perforation in typhoid fever
Aziz Sümer, Özgür Kemik, Ahmet Cumhur Dülger, Aydemir Olmez, Ismail Hasirci, Erol Kişli, Vedat Bayrak, Gulay Bulut, Çetin Kotan
Aziz Sümer, Özgür Kemik, Aydemir Olmez, Ismail Hasirci, Erol Kişli, Vedat Bayrak, Çetin Kotan, Department of General Surgery, Medical Faculty, University of Yüzüncü Yıl, Van, 6500, Turkey
Ahmet Cumhur Dülger, Department of Gastroenterology, Medical Faculty, University of Yüzüncü Yıl, Van, 6500, Turkey
Gulay Bulut, Department of Pathology, Medical Faculty, University of Yüzüncü Yıl, Van, 6500, Turkey
Author contributions: Sümer A collected and analyzed the data and wrote the paper; Kemik Ö, Kişli E, Dülger AC, Bayrak V and Kotan Ç contributed to the discussion; Kişli E, Bayrak V and Kotan Ç performed the surgical operations; Bulut G performed the pathological evaluation; Olmez A and Hasirci I collected the data.
Correspondence to: Aziz Sümer, MD, Assistant Professor, Department of General Surgery, Medical Faculty, University of Yüzüncü Yıl, Van, 6500, Turkey. azizsumer2002@yahoo.com
Telephone: +90-432-2251024 Fax: +90-432-2164705
Received: May 10, 2010
Revised: June 6, 2010
Accepted: June 13, 2010
Published online: September 7, 2010
Abstract

AIM: To represent our clinical experience in the treatment of intestinal perforation arising from typhoid fever.

METHODS: The records of 22 surgically-treated patients with typhoid intestinal perforation were evaluated retrospectively.

RESULTS: There were 18 males and 4 females, mean age 37 years (range, 8-64 years). Presenting symptoms were fever, abdominal pain, diarrhea or constipation. Sixteen cases were subjected to segmental resection and end-to-end anastomosis, while 3 cases received 2-layered primary repair following debridement, one case with multiple perforations received 2-layered primary repair and end ileostomy, one case received segmental resection and end-to-end anastomosis followed by an end ileostomy, and one case received segmental resection and end ileostomy with mucous fistula operation. Postoperative morbidity was seen in 5 cases and mortality was found in one case.

CONCLUSION: Intestinal perforation resulting from Salmonella typhi is an important health problem in Eastern and Southeastern Turkey. In management of this illness, early and appropriate surgical intervention is vital.

Keywords: Intestinal perforation; Typhoid fever; Treatment