Case Report
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World J Gastroenterol. Jan 7, 2010; 16(1): 131-135
Published online Jan 7, 2010. doi: 10.3748/wjg.v16.i1.131
Biliary cystadenocarcinoma diagnosed with real-time contrast-enhanced ultrasonography: Report of a case with diagnostic features
Xiao-Long Ren, Rui-Ling Yan, Xiao-Hui Yu, Ying Zheng, Jun-E Liu, Xiao-Bin Hou, Si-Yang Zuo, Xiao-Yan Fu, Hong Chang, Jian-Hong Lu
Xiao-Long Ren, Rui-Ling Yan, Xiao-Hui Yu, Ying Zheng, Jun-E Liu, Xiao-Bin Hou, Si-Yang Zuo, Xiao-Yan Fu, Hong Chang, Jian-Hong Lu, Department of Ultrasonography, General Hospital of Lanzhou Military Area Command, 333 Binhe South Road, Lanzhou 730050, Gansu Province, China
Author contributions: Ren XL and Yan RL performed the contrast enhanced ultrasound work and analysis; Yu XH, Zheng Y, Liu JE, Hou XB, Zuo SY, Fu XY, Chang H and Lu JH co-ordinated and provided the collection of all the human material and clinical materials; Ren XL designed the study and wrote the manuscript.
Correspondence to: Xiao-Long Ren, MD, PhD, Department of Ultrasonography, General Hospital of Lanzhou Military Area Command, 333 Binhe South Road, Lanzhou 730050, Gansu Province, China. renxiaolong70@hotmail.com
Telephone: +86-931-8994574 Fax: +86-931-8994575
Received: October 2, 2009
Revised: November 6, 2009
Accepted: November 13, 2009
Published online: January 7, 2010
Abstract

Biliary cystadenocarcinoma is a very rare malignant cystic tumor of the liver, which is often misdiagnosed due to a poor recognition of it. We report a case of a 60-year-old man with biliary cystadenocarcinoma with his real time contrast enhanced ultrasound (CEUS) characteristics compared to those of computed tomography (CT) and magnetic resonance imaging (MRI), which were correlated with the surgical and pathologic findings. Cystic wall enhancement, internal septations and intra-cystic solid portions in the arterial phase were observed on CEUS after contrast agent injection. The enhancement was washed out progressively and depicted as hypo-enhancement in the portal and late phases. CT revealed a large irregular cystic lesion in the left liver lobe with no clear septations and solid components. MRI showed an irregular cystic occupying lesion with septations.

Keywords: Biliary cystadenocarcinoma; Cystic neoplasm; Hepatic disease; Contrast medium; Ultrasonography