Original Article
Copyright ©2009 The WJG Press and Baishideng. All rights reserved.
World J Gastroenterol. Nov 14, 2009; 15(42): 5266-5273
Published online Nov 14, 2009. doi: 10.3748/wjg.15.5266
Validation of Fujinon intelligent chromoendoscopy with high definition endoscopes in colonoscopy
Adolfo Parra-Blanco, Alejandro Jiménez, Björn Rembacken, Nicolás González, David Nicolás-Pérez, Antonio Z Gimeno-García, Marta Carrillo-Palau, Takahisa Matsuda, Enrique Quintero
Adolfo Parra-Blanco, David Nicolás-Pérez, Antonio Z Gimeno-García, Marta Carrillo-Palau, Enrique Quintero, Department of Gastroenterology, University Hospital of the Canary Islands, c/ Ofra s/n, La Laguna 38320, Tenerife, Spain
Adolfo Parra-Blanco, Department of Gastroenterology, Hospital Universitario Central de Asturias, Celestino Villamil s/n, 33006 Oviedo, Principado de Asturias, Spain
Alejandro Jiménez, Research Unit, University Hospital of the Canary Islands, c/ Ofra s/n, La Laguna 38320, Tenerife, Spain
Björn Rembacken, Centre for Digestive Diseases, The General Infirmary at Leeds, Great George St, Leeds, LS1 3EX, United Kingdom
Nicolás González, Department of Gastroenterology, Hospital de Clínicas de Montevideo, Avda. Italia s/n, Montevideo 11600, Uruguay
Takahisa Matsuda, Division of Endoscopy, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
Author contributions: Parra-Blanco A designed the research; Parra-Blanco A, Jiménez A, González N, Nicolás-Pérez D, Gimeno-García AZ, Carrillo-Palau M, Matsuda T and Quintero E performed the research; Parra-Blanco A, Jiménez A and Quintero E analyzed the data; the manuscript was drafted by Parra-Blanco A, González N, Rembacken B, and Quintero E; and all authors read and approved the final manuscript.
Supported by Consejería de Educación, Cultura y Deportes, Gobierno de Canarias PI2002/138, the Instituto de Salud Carlos III C03/02
Correspondence to: Adolfo Parra-Blanco, MD, PhD, Head of the Endoscopy Unit, Department of Gastroenterology, Hospital Universitario Central de Asturias, Celestino Villamil s/n, 33006 Oviedo, Principado de Asturias, Spain. parrablanco@hotmail.com
Telephone: +34-985-108000 Fax: +34-985-273614
Received: August 14, 2009
Revised: September 21, 2009
Accepted: September 28, 2009
Published online: November 14, 2009
Abstract

AIM: To validate high definition endoscopes with Fujinon intelligent chromoendoscopy (FICE) in colonoscopy.

METHODS: The image quality of normal white light endoscopy (WLE), that of the 10 available FICE filters and that of a gold standard (0.2% indigo carmine dye) were compared.

RESULTS: FICE-filter 4 [red, green, and blue (RGB) wavelengths of 520, 500, and 405 nm, respectively] provided the best images for evaluating the vascular pattern compared to white light. The mucosal surface was best assessed using filter 4. However, the views obtained were not rated significantly better than those observed with white light. The “gold standard”, indigo carmine (IC) dye, was found to be superior to both white light and filter 4. Filter 6 (RGB wavelengths of 580, 520, and 460 nm, respectively) allowed for exploration of the IC-stained mucosa. When assessing mucosal polyps, both FICE with magnification, and magnification following dye spraying were superior to the same techniques without magnification and to white light imaging. In the presence of suboptimal bowel preparation, observation with the FICE mode was possible, and endoscopists considered it to be superior to observation with white light.

CONCLUSION: FICE-filter 4 with magnification improves the image quality of the colonic vascular patterns obtained with WLE.

Keywords: Colonoscopy; Computed virtual chromoendoscopy; Fujinon intelligent chromoendoscopy; Magnifying colonoscopy; Polyp diagnosis