Gong DJ, Miao CF, Bao Q, Jiang M, Zhang LF, Tong XT, Chen L. Risk factors for operative morbidity and mortality in gastric cancer patients undergoing total gastrectomy. World J Gastroenterol 2008; 14(42): 6560-6563 [PMID: 19030212 DOI: 10.3748/wjg.14.6560]
Corresponding Author of This Article
Li Chen, Department of Surgery, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China. chenli@mail.hz.zj.cn
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Rapid Communication
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World J Gastroenterol. Nov 14, 2008; 14(42): 6560-6563 Published online Nov 14, 2008. doi: 10.3748/wjg.14.6560
Risk factors for operative morbidity and mortality in gastric cancer patients undergoing total gastrectomy
Dao-Jun Gong, Chao-Feng Miao, Qi Bao, Ming Jiang, Li-Fang Zhang, Xiao-Tao Tong, Li Chen
Dao-Jun Gong, Chao-Feng Miao, Qi Bao, Ming Jiang, Li-Fang Zhang, Xiao-Tao Tong, Li Chen, Department of Surgery, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
Author contributions: Gong DJ and Chen L designed the study; Gong DJ, Miao CF, Bao Q, and Jiang M performed the study; Miao CF, Zhang LF, Tong XT, and Jiang M analyzed the data; Gong DJ wrote the paper.
Supported by Grants from the Foundation of Science and Technology Department of Zhejiang Province, China, No. 2004C34010
Correspondence to: Li Chen, Department of Surgery, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China. chenli@mail.hz.zj.cn
Telephone: +86-571-86022246 Fax: +86-571-87022776
Received: August 9, 2008 Revised: September 16, 2008 Accepted: September 23, 2008 Published online: November 14, 2008
Abstract
AIM: To study the risk factors for morbidity and mortality following total gastrectomy.
METHODS: We retrospectively reviewed the records of 125 consecutive patients who underwent total gastrectomy for gastric cancer at the Second Affiliated Hospital of Zhejiang University School of Medicine between January 2003 and March 2008.
RESULTS: The overall morbidity rate was 20.8% (27 patients) and the mortality rate was 3.2% (4 patients). Morbidity rates were higher in patients aged over 60 [odds ratio (OR) 4.23 (95% confidence interval (CI) 1.09 to 12.05)], with preoperative comorbidity [with vs without, OR 1.25 (95% CI 1.13 to 8.12)], when the combined resection was performed [combined resection vs total gastrectomy only, OR 2.67 (95% CI 1.58 to 5.06)].
CONCLUSION: Age, preoperative comorbidity and combined resection were independently associated with the rate of morbidity after total gastrectomy for gastric cancer.
