Case Report
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World J Gastroenterol. Jan 28, 2007; 13(4): 647-648
Published online Jan 28, 2007. doi: 10.3748/wjg.v13.i4.647
Cytomegalovirus hepatitis and myopericarditis
Leire Zubiaurre, Eva Zapata, Luis Bujanda, María Castillo, Igor Oyarzabal, Maria A Gutiérrez-Stampa, Angel Cosme
Leire Zubiaurre, Eva Zapata, Luis Bujanda, Angel Cosme, Department of Digestive disease, Hospital Donostia, Spain
María Castillo, Department of Cardiology, Hospital Donostia, Spain
Igor Oyarzabal, Department of Urology. Hospital Donostia, Spain
Maria A Gutiérrez-Stampa, Department of General Medicine, Donostia, Spain
Author contributions: All authors contributed equally to the work.
Correspondence to: Leire Zubiaurre, Department of Digestive disease, Hospital Donostia, Paseo Beguiristain S/N, 20014 San Sebastián (Gipúzcoa), Spain. leirezubi@yahoo.es
Telephone: +34-985-943007173 Fax: +34-985-943007065
Received: May 23, 2006
Revised: June 3, 2006
Accepted: June 15, 2006
Published online: January 28, 2007
Abstract

Cytomegalovirus (CMV) infection in inmunocompetent hosts generally is asymptomatic or may present as a mononucleosis syndrome but rarely can lead to severe organ complications. We report a case of simultaneous hepatic and pericardic CMV infection in a 36-year old immunocompetent man. He was admitted to coronary unit with fever, chest pain radiated to shoulders, changes on electrocardiogram with diffuse ST elevation and modest laboratory elevations in the MB fraction of creatine kinase (CK-MB) of 33.77 μg/L (0.1-6.73), serum cardiac troponin T of 0.904 ng/mL (0-0.4), creatine kinase of 454 U/L (20-195) and myoglobin of 480.4 μg/L (28-72). Routine laboratory test detected an elevation of aminotransferase level: alanine aminotransferase 1445 U/L, aspartate aminotransferase 601 U/L. We ruled out other causes of hepatitis with normal results except IgM CMV. The patient was diagnosed with myopericarditis and hepatitis caused by cytomegalovirus and started symptomatic treatment with salicylic acid. In few days the laboratory findings became normal and the patient was discharged.

Keywords: Cytomegalovirus; Hepatitis; Myopericarditis; Pericarditis