Case Report
Copyright ©2007 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Sep 14, 2007; 13(34): 4653-4654
Published online Sep 14, 2007. doi: 10.3748/wjg.v13.i34.4653
Eosinophilic gastroenteritis with cytomegalovirus infection in an immunocompetent child
Junji Takeyama, Daiki Abukawa, Katsushi Miura
Junji Takeyama, Department of Pathology, Miyagi Children’s Hospital, Sendai 989-3126, Japan
Daiki Abukawa, Katsushi Miura, Department of General Pediatrics, Miyagi Children’s Hospital, Sendai 989-3126, Japan
Author contributions: All authors contributed equally to the work.
Correspondence to: Junji Takeyama, Department of Pathology, Miyagi Children’s Hospital, 4-3-17 Ochiai, Aoba-ku, Sendai 989-3126, Japan. jtakeyama@miyagi-children.or.jp
Telephone: +81-22-3915111 Fax: +81-22-3915118
Received: May 17, 2007
Revised: June 2, 2007
Accepted: June 9, 2007
Published online: September 14, 2007
Abstract

A 3-year-old boy developed transient protein-losing gastroenteropathy associated with cytomegalovirus (CMV) infection. Both IgG and IgM antibodies to CMV were positive in a serologic blood test. Upper gastrointestinal endoscopy showed multiple erosions throughout the body of the stomach, without enlarged gastric folds. Histological examination of the biopsy specimens indicated eosinophilic gastroenteritis and CMV infection. The patient had complete resolution without specific therapy for CMV in four weeks. An allergic reaction as well as CMV infection played important roles in the pathogenesis of this case.

Keywords: Eosinophilic gastroenteritis; Cytomegalovirus; Protein-losing gastroenteropathy; Allergy; Menetrier’s disease