Case Report
Copyright ©2007 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Apr 7, 2007; 13(13): 2002-2003
Published online Apr 7, 2007. doi: 10.3748/wjg.v13.i13.2002
Treatment of pediatric Ogilvie’s syndrome with low-dose erythromycin: A case report
Yu-Bo Zhang, Sheng-Yang Guan, Zhao-Zhu Li, Da-Peng Jiang
Da-Peng Jiang, Zhao-Zhu Li, Sheng-Yang Guan, Yu-Bo Zhang, Department of Pediatric Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Da-Peng Jiang, Department of Pediatric Surgery, Second Affiliated Hospital of Harbin Medical University, #246 Xuefu Road, Harbin 150086, Heilongjiang Province, China. jdp509@163.com
Telephone: +86-451-86605247
Received: January 18, 2007
Revised: February 15, 2006
Accepted: March 5, 2007
Published online: April 7, 2007
Abstract

Acute colonic pseudo-obstruction is a poorly understood syndrome, characterized by the signs, symptoms and radiological pattern of a large bowel obstruction without evidence for a mechanical obstruction. We report a case of a 2-year old boy who presented with progressive abdominal distention, vomiting and abdominal pain on postoperative d 3. Plain abdominal Χ-ray showed markedly dilated large bowel. Mechanical colonic obstruction was ruled out with hypaque enema. Ogilvie’s syndrome was suspected. The patient received treatment with oral erythromycin which had an immediate beneficial effect. During the 6 mo follow-up, no recurrences of symptoms were observed. We provide a safe and effective therapy for Ogilvie’s syndrome in pediatric individuals.

Keywords: Acute colonic pseudo-obstruction; Erythromycin; Abdominal distention; Prokinetic agent