Jun DW, Lee OY, Yoon HJ, Lee SH, Lee HL, Choi HS, Yoon BC, Lee MH, Lee DH, Cho SH. Food intolerance and skin prick test in treated and untreated irritable bowel syndrome. World J Gastroenterol 2006; 12(15): 2382-2387 [PMID: 16688829 DOI: 10.3748/wjg.v12.i15.2382]
Corresponding Author of This Article
Oh-Young Lee, Department of Internal Medicine, College of Medicine, Hanyang University Hospital, Seoul, South Korea 17 Haengdang-dong, Sungdong-ku, Seoul 133-791, Korea. leeoy@hanyang.ac.kr
Article-Type of This Article
Clinical Research
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Dae-Won Jun, Oh-Young Lee, Ho-Joo Yoon, Hang-Lak Lee, Ho-Soon Choi, Byung-Chul Yoon, Min-Ho Lee, Dong-Hoo Lee, Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea
Seok-Hwa Lee, Department of Food and Nutrition, College of Human Ecology, Hanyang University, Seoul, Korea
Sang-Hoen Cho, Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, South Korea
Supported by a grant from the Korea Society of Neurogastroenterology and Motility Research Funds (project No. 2003530).
Correspondence to: Oh-Young Lee, Department of Internal Medicine, College of Medicine, Hanyang University Hospital, Seoul, South Korea 17 Haengdang-dong, Sungdong-ku, Seoul 133-791, Korea. leeoy@hanyang.ac.kr
Telephone: +82-2-22908343 Fax: +82-2-2298-9183
Received: July 23, 2005 Revised: October 9, 2005 Accepted: October 10, 2005 Published online: April 21, 2006
Abstract
AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens.
METHODS: We recruited 105 subjects to form three different target groups: treated group (n = 44) undergoing treatment for IBS, untreated group (n = 31) meeting the Rome II criteria without treatment for IBS, control group (n = 30) with no IBS symptoms.
RESULTS: SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P < 0.01). The number of positive SPTs was greater in the IBS group than in the control group (P < 0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P = 0.03).
CONCLUSION: Positive food SPT is higher in IBS patients than in controls.
