Copyright
©2006 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 14, 2006; 12(10): 1509-1510
Published online Mar 14, 2006. doi: 10.3748/wjg.v12.i10.1509
Published online Mar 14, 2006. doi: 10.3748/wjg.v12.i10.1509
Exacerbation of inflammatory bowel disease by nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors: Fact or fiction?
Mario Guslandi, Gastroenterology Unit, S.Raffaele University Hospital, Via Olgettina 60, Milano 20132, Italy
Correspondence to: Professor Mario Guslandi, Gastroenterology Unit, S.Raffaele University Hospital, Via Olgettina 60, Milano 20132, Italy. guslandi.mario@hsr.it
Telephone: +39-02-26431 Fax: +39-02-26433491
Received: June 21, 2005
Revised: July 12, 2005
Accepted: July 22, 2005
Published online: March 14, 2006
Revised: July 12, 2005
Accepted: July 22, 2005
Published online: March 14, 2006
Abstract
The existence of a possible link between inflammatory bowel disease (IBD) and nonsteroidal anti-inflammatory drugs (NSAIDs) has been repeatedly suggested. Recently, a few studies have addressed the issue of a possible, similar effect by selective cyclooxygenase-2 inhibitors (COXIBs). The present article reviews the available scientific evidence for this controversial subject.