Brief Reports
Copyright ©The Author(s) 2005. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 21, 2005; 11(27): 4254-4257
Published online Jul 21, 2005. doi: 10.3748/wjg.v11.i27.4254
Immunization of mice with concentrated liquor from male zooid of Antheraea pernyi
Sheng Li, Bo Zhang, Wei-Dong Zhang, Ting-Hang Ma, Yong Huang, Long-Hai Yi, Jin-Ming Yu
Sheng Li, Bo Zhang, Ting-Hang Ma, Yong Huang, Long-Hai Yi, Jin-Ming Yu, Shandong Tumor Hospital, Jinan 250117, Shandong Province, China
Wei-Dong Zhang, Basic Medical Institute of Shandong Academy of Medical Sciences, Jinan 250062, Shandong Province, China Supported by the National Natural Science Foundation of China, No. 30472260
Author contributions: All authors contributed equally to the work.
Correspondence to: Sheng Li, Shandong Tumor Hospital, Jinan 250117, Shandong Province, China. drlisheng@sohu.com
Telephone: Fax: +86-531-8550649
Received: November 2, 2004
Revised: December 20, 2004
Accepted: December 21, 2004
Published online: July 21, 2005
Abstract

AIM: To study the effects of concentrated liquor from male zooid of Antheraea pernyi on immunological mice.

METHODS: For each experiment, 40 mice were randomly divided into normal saline group (control group) and three tested groups that were administered different dosages of concentrated liquor from male zooid of A. pernyi and food for 15 d. The typical FSR and HC50 value, monocyte-phagocytic exponent K and emendated monocyte-phagocytic exponent α were determined and calculated respectively.

RESULTS: After 24 and 48 h, the FSR values of the three tested groups improved significantly in comparison to the control group by variance analysis. The HC50 values showed a significant difference between the high dosage group and the control group, as well as between the high dosage group and other two tested groups. The monocyte-phagocytic exponent K and emendated exponent α showed rising tendencies, but no significant differences were found by variance analysis.

CONCLUSION: The concentrated liquor from male zooid of A. pernyi can significantly enhance cellular and humoral immune function in mice, but has no distinct influence on the monocyte-phagocytic system in mice.

Keywords: Antheraea pernyi; Male zooid; Concentrated liquor; Mice; Immune function