Brief Reports
Copyright ©2005 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 28, 2005; 11(16): 2513-2517
Published online Apr 28, 2005. doi: 10.3748/wjg.v11.i16.2513
A randomized controlled trial of laparoscopic versus open cholecystectomy in patients with cirrhotic portal hypertension
Wu Ji, Ling-Tang Li, Zhi-Ming Wang, Zhu-Fu Quan, Xun-Ru Chen, Jie-Shou Li
Wu Ji, Ling-Tang Li, Zhi-Ming Wang, Zhu-Fu Quan, Jie-Shou Li, Research Institute of General Surgery, Nanjing General Hospital of Nanjing PLA Command Area, Nanjing 210002, Jiangsu Province, China
Xun-Ru Chen, Department of Hepatobiliary Surgery, Kunming General Hospital of Chengdu PLA Command Area, Kunming 650032, Yunnan Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Professor Jie-Shou Li, Research Institute of General Surgery, Nanjing General Hospital of Nanjing PLA Command Area, 305 Eastern Zhongshan Road, Nanjing 210002, Jiangsu Province, China. lijiesou@public1.ptt.js.cn
Telephone: +86-25-80860065 Fax: +86-25-4803956
Received: March 5, 2003
Revised: March 6, 2003
Accepted: May 13, 2004
Published online: April 28, 2005
Abstract

AIM: To evaluate the characters, risks and benefits of laparoscopic cholecystectomy (LC) in cirrhotic portal hypertension (CPH) patients.

METHODS: Altogether 80 patients with symptomatic gallbladder disease and CPH, including 41 Child class A, 32 Child class B and 7 Child class C, were randomly divided into open cholecystectomy (OC) group (38 patients) and LC group (42 patients). The cohorts were well-matched for number, age, sex, Child classification and types of disease. Data of the two groups were collected and analyzed.

RESULTS: In LC group, LC was successfully performed in 36 cases, and 2 patients were converted to OC for difficulty in managing bleeding under laparoscope and dense adhesion of Calot’s triangle. The rate of conversion was 5.3%. The surgical duration was 62.6±15.2 min. The operative blood loss was 75.5±15.5 mL. The time to resume diet was 18.3±6.5 h. Seven postoperative complications occurred in five patients (13.2%). All patients were dismissed after an average of 4.6±2.4 d. In OC group, the operation time was 60.5±17.5 min. The operative blood loss was 112.5±23.5 mL. The time to resume diet was 44.2±10.5 h. Fifteen postoperative complications occurred in 12 patients (30.0%). All patients were dismissed after an average of 7.5±3.5 d. There was no significant difference in operation time between OC and LC group. But LC offered several advantages over OC, including fewer blood loss and lower postoperative complication rate, shorter time to resume diet and shorter length of hospitalization in patients with CPH.

CONCLUSION: Though LC for patients with CPH is difficult, it is feasible, relatively safe, and superior to OC. It is important to know the technical characters of the operation, and pay more attention to the meticulous perioperative managements.

Keywords: LC; CPH; OC