Lee SK, Lee YC, Chung JB, Chon CY, Moon YM, Kang JK, Park IS, Suh CO, Yang WI. Low grade gastric MALTOMA: Treatment strategies based on 10 year follow-up. World J Gastroenterol 2004; 10(2): 223-226 [PMID: 14716827 DOI: 10.3748/wjg.v10.i2.223]
Corresponding Author of This Article
Dr. Jae Bock Chung, Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, South Korea. jbchung@ yumc.yonsei.ac.kr
Article-Type of This Article
H Pylori
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World J Gastroenterol. Jan 15, 2004; 10(2): 223-226 Published online Jan 15, 2004. doi: 10.3748/wjg.v10.i2.223
Low grade gastric MALTOMA: Treatment strategies based on 10 year follow-up
Sang Kil Lee, Yong Chan Lee, Jae Bock Chung, Chae Yoon Chon, Young Myoung Moon, Jin Kyung Kang, In-Suh Park, Chang Ok Suh, Woo Ik Yang
Sang Kil Lee, Yong Chan Lee, Jae Bock Chung, Chae Yoon Chon, Young Myoung Moon, Jin Kyung Kang, Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
In-Suh Park, Department of Internal Medicine, NHIC Ilsan Hospital, Ilsan, South Korea
Chang Ok Suh, Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, South Korea
Woo Ik Yang, Department of Pathology, Yonsei University College of Medicine, Seoul, South Korea
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Jae Bock Chung, Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, South Korea. jbchung@ yumc.yonsei.ac.kr
Telephone: +82-2-361-5410 Fax: +82-2-393-6884
Received: July 17, 2003 Revised: September 17, 2003 Accepted: September 24, 2003 Published online: January 15, 2004
Abstract
AIM: To deduce strategic guideline of gastric mucosa associated lymphoid tissue lymphoma (MALTOMA) by evaluating the long-term outcome of patients in respect to various treatment modalities.
METHODS: A total of 55 patients with MALTOMA from May 1992 to August 2002 were retrospectively reviewed.
RESULTS: Complete remission was obtained in 24 (82.8%) of 29 patients treated with anti Helicobacter pylori (H pylori) regimen only. The duration to reach complete remission was 12 months (85 percentile, 2-33 months). Five patients showed complete remission with radiation therapy (26-86 months). Two of them were H pylori treatment failure cases.
CONCLUSION: H pylori eradication is an effective primary treatment option for low grade MALTOMA and radiation therapy could be considered in patients with no evidence of H pylori infection or who do not respond to H pylori eradication therapy 12 months after successful eradication.
