Clinical Research
Copyright ©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 15, 2004; 10(12): 1798-1801
Published online Jun 15, 2004. doi: 10.3748/wjg.v10.i12.1798
Severity of gastroesophageal reflux disease influences daytime somnolence: A clinical study of 134 patients underwent upper panendoscopy
Pál Demeter, Katalin Várdi Visy, Nóra Gyulai, Róbert Sike, Tamás G Tóth, János Novák, Pál Magyar
Pál Demeter, Róbert Sike, Tamás G Tóth, Outpatient Clinic of Gastroenterology, St. John’s Hospital, Budapest, Hungary
Katalin Várdi Visy, Nóra Gyulai, Pál Magyar, Department of Pulmonology, Semmelweis Medical University, Budapest, Hungary
János Novák, Dept. of Internal Medicine and Gastroenterology, Pandy Hospital, Gyula, Békés County, Hungary
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr. Pál Demeter, St. John’s Hospital, Outpatient Clinic of Gastroenterology, Szõlõskertút 7, Budakeszi 2092, Hungary. pauldemeter@axelero.hu
Telephone: +36-30-9222985 Fax: +36-23-457656
Received: December 10, 2003
Revised: January 9, 2004
Accepted: January 16, 2004
Published online: June 15, 2004
Abstract

AIM: To asses the relationship between severity of gastroesophageal refluxe disease and Epworth sleepiness scale as an indicator of daytime somnolence.

METHODS: One hundred and thirty-four patients underwent an upper panendoscopy as indicated by the typical reflux symptoms and were also investigated with regard to somnolence. Sleepiness was evaluated by Epworth Sleepiness Scale, which was compared to the severity of endoscopic findings (Savary-Miller/modified by Siewert). Patients with psychiatric disorders or being on sedato-hypnotics as well as shift workers were excluded from the study. The relationship between the severity of the reflux disease and daytime somnolence was analyzed with the help of multivariate regression analysis.

RESULTS: A positive tendency was found between the severity of the reflux disease and the corresponding Epworth Sleepiness Scale. In the case of the more severe type-Savary-Miller III-at least a mild hypersomnia was found. For this group daytime somnolence was significantly higher than in the case of the non-erosive type of Gastroesophageal Reflux Disease representing the mildest stage of reflux disease.

CONCLUSION: The severity of Gastroesophageal Reflux Disease influences daytime somnolence.

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