Clinical Research
Copyright ©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jan 1, 2004; 10(1): 122-126
Published online Jan 1, 2004. doi: 10.3748/wjg.v10.i1.122
Effects of exercise on lipid metabolism and musculoskeletal fitness in female athletes
Kung-Tung Chen, Rong-Sen Yang
Kung-Tung Chen, Department of Genenal Education, Ming Hsin University of Science and Technology, Hsinchu 304, Taiwan, China
Rong-Sen Yang, Department of Orthopaedics, College of Medicine, National Taiwan University, Taipei 10043, Taiwan, China
Author contributions: All authors contributed equally to the work.
Supported by the National Science Council of Taiwan, NSC91-2413-H-159-001
Correspondence to: Dr. Rong-Sen Yang, Department of Orthopaedics, National Taiwan University Hospital, No.7 Chung-Shan South Road, Taipei 10043, Taiwan, China. yang@ha.mc.ntu.edu.tw
Telephone: +886-2-2312-3456 Ext 3958 Fax: +886-2-23936577
Received: October 16, 2003
Revised: October 20, 2003
Accepted: November 20, 2003
Published online: January 1, 2004
Abstract

AIM: This study investigated the effects of intense training on lipid metabolism, bone metabolism and bone mineral density (BMD) in female athletes.

METHODS: Sixty-six female subjects participated in this study, age ranging from 18 to 55 years. The sample group included thirty-six athletic subjects and the control group comprised thirty non-athletic individuals. Five athletes competed with national level (5/36) and nine non-athletic subjects (9/30) were postmenopausal women. The assessment items included body composition, radius BMD, calcaneus BMD, lung function, muscular endurance, renal and liver function, bone marker assay and hormone status. All data were analysed, using SPSS 10.0 software, and were presented as mean rank statistical difference, using the Kurskal-Wallis (K-W) test. After that the non-parameter statistics were used. Either K value or P value below 0.05 was considered significant.

RESULTS: Urine deoxypyridinoline/creatinine (Dpd/Cre) levels increased significantly (5.93 ± 2.31 vs 6.85 ± 1.43, K < 0.01), sit-reach (29.30 ± 9.48 cm vs 41.31 ± 9.43 cm, K < 0.001, P < 0.001), 1 minute sit-ups with bended knees (1 min sit-ups) (17.60 ± 9.34 count vs 30.00 ± 10.38 count, K < 0.001, P < 0.001), and vertical jump (25.27 ± 6.63 cm vs 34.69 ± 7.99 cm, K < 0.001, P < 0.001) improved significantly in the athletes group. The athletes group also had a significantly increased level of estriol (E3) (0.14 ± 0.13 pg/mL vs 0.07 ± 0.04 pg/mL, K < 0.01, P < 0.01), radius BMD (1.37 ± 0.49 gm/cm2vs 1.19 ± 0.40 gm/cm2, K < 0.05) and calcaneus BMD (0.57 ± 0.17 gm/cm2vs -0.20 ± 0.17 gm/cm2, K < 0.01, P < 0.05) compared with those of the controls. The high density lipoprotein (HDL) (65.00 ± 14.02 mg/dL vs 52.26 ± 4.84 mg/dL, K < 0.05, P < 0.05) was significantly lower in postmenopausal inactive athletes (5/36) than premenopausal active athletes (31/36). On the other hand, low-density lipoprotein (LDL) (98.35 ± 23.84 mg/dL vs 131.00 ± 21.63 mg/dL, K < 0.05, P < 0.01), cholesterol (CHO) (164.03 ± 27.01 mg/dL vs 193.00 ± 23.48 mg/dL, K < 0.05, P < 0.05), triglyceride (TG) (63.00 ± 26.39 mg/dL vs 147.00 ± 87.21 mg/dL, K < 0.01), body fat % (BF%) (28.16 ± 4.90% vs 34.84 ± 4.44%, K < 0.05, P < 0.001) and body mass index (BMI) (21.98 ± 2.98 kg/m2vs 26.42 ± 5.01 kg/m2, K < 0.05, P < 0.001) were significantly higher in postmenopausal inactive athletes (5/36) than premenopausal active athletes (31/36). TG (90.22 ± 39.82 mg/dL vs 147.00 ± 87.21 mg/dL), CHO (186.44 ± 24.90 mg/dL vs 193.00 ± 23.48 mg/dL) were higher, but the HDL was significantly lower (62.18 ± 10.68 mg/dL vs 52.26 ± 4.84 mg/dL, P < 0.05) in postmenopausal athletes (5/36) group than in postmenopausal control group (9/30).

CONCLUSION: Postmenopausal athletes (5/36) who no longer took competing exercises had reduced levels of physical activity, faced increased risk of cardiovascular disease compared to active athletes (31/36) and the postmenopausal controls (9/30). We may thus concluded that long term exercise effectively improves musculoskeletal fitness and prevents BMD loss in female athletes.

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