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For: Huang XH, Sun LH, Lu DD, Sun Y, Ma LJ, Zhang XR, Huang J, Yu L. Codon 249 mutation in exon 7 of p53 gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China. World J Gastroenterol 2003; 9(4): 692-695 [PMID: 12679912 DOI: 10.3748/wjg.v9.i4.692]
URL: https://www.wjgnet.com/1007-9327/full/v9/i4/692.htm
Number Citing Articles
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Qianwei Ye, Sunbin Ling, Shusen Zheng, Xiao Xu. Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNAMolecular Cancer 2019; 18(1) doi: 10.1186/s12943-019-1043-x
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Emily Crowley, Federica Di Nicolantonio, Fotios Loupakis, Alberto Bardelli. Liquid biopsy: monitoring cancer-genetics in the bloodNature Reviews Clinical Oncology 2013; 10(8) doi: 10.1038/nrclinonc.2013.110
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Muhammad Nur Adam Hatta, Ezanee Azlina Mohamad Hanif, Siok-Fong Chin, Hui-min Neoh. Pathogens and Carcinogenesis: A ReviewBiology 2021; 10(6) doi: 10.3390/biology10060533
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Kai-Zong Li, Ke-Feng Dou, Yan-Ling Yang, Shu-Qiang Yue. Expression of PCNA and CD44mRNA in colorectal cancer with venous invasion and its relationship to liver metastasisWorld Journal of Gastroenterology 2003; 9(12): 2863-2865 doi: 10.3748/wjg.v9.i12.2863
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Huai Wang, Peng Liao, Shelya X Zeng, Hua Lu. It takes a team: a gain-of-function story of p53-R249SJournal of Molecular Cell Biology 2019; 11(4) doi: 10.1093/jmcb/mjy086
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Jingjing Jiao, Weibo Niu, Ying Wang, Keith Baggerly, Yuanqing Ye, Xifeng Wu, Dewitt Davenport, Jose Luis Almeda, Monica M. Betancourt-Garcia, R. Armour Forse, Heather L. Stevenson, Gordon P. Watt, Joseph B. McCormick, Susan P. Fisher-Hoch, Laura Beretta. Prevalence of Aflatoxin-Associated TP53R249S Mutation in Hepatocellular Carcinoma in Hispanics in South TexasCancer Prevention Research 2018; 11(2) doi: 10.1158/1940-6207.CAPR-17-0235
7
Filiz Türe Özdemir, Arzu Tiftikci, Seda Sancak, Fatih Eren, Veysel Tahan, Hakan Akın, Feyza Gündüz, Ala Eldeen Kedrah, Yücel Üstündağ, Erol Avşar, Nurdan Tözün, Osman Özdoğan. The Prevalence of the Mutation in Codon 249 of the P53 Gene in Patients with Hepatocellular Carcinoma (HCC) in TurkeyJournal of Gastrointestinal Cancer 2010; 41(3) doi: 10.1007/s12029-010-9140-5
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Peng Lee, Shilpa Jain, Matthew R. Pincus, Ruliang Xu. Henry's Clinical Diagnosis and Management by Laboratory Methods2011;  doi: 10.1016/B978-1-4377-0974-2.00076-2
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Jian-Guo Chen, Thomas W. Kensler, Gui-Ju Sun, Jian Zhu, Jian-Hua Lu, Da Pan, Yong-Hui Zhang, John D. Groopman. Aflatoxin and Liver Cancer in China: The Evolving Research LandscapeToxins 2026; 18(2) doi: 10.3390/toxins18020061
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S. Anitha, D. Raghunadharao, F. Waliyar, H. Sudini, M. Parveen, Ratna Rao, P. Lava Kumar. The association between exposure to aflatoxin, mutation in TP53, infection with hepatitis B virus, and occurrence of liver disease in a selected population in Hyderabad, IndiaMutation Research/Genetic Toxicology and Environmental Mutagenesis 2014; 766 doi: 10.1016/j.mrgentox.2013.12.011
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Vincent L. Chen, Neehar D. Parikh. Liquid Biopsy for Hepatocellular CarcinomaCurrent Hepatology Reports 2019; 18(4) doi: 10.1007/s11901-019-00491-z
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Ying-Hsiu Su, Selena Y Lin, Wei Song, Surbhi Jain. DNA markers in molecular diagnostics for hepatocellular carcinomaExpert Review of Molecular Diagnostics 2014; 14(7) doi: 10.1586/14737159.2014.946908
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Jia Jie Li, Yanqing Lv, Huifan Ji. Diagnostic performance of circulating tumor DNA as a minimally invasive biomarker for hepatocellular carcinoma: a systematic review and meta-analysisPeerJ 2022; 10 doi: 10.7717/peerj.14303
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GERALD C KIMBI, MICHAEL C KEW, MIMI C YU, KAZUKO ARAKAWA, JOHN HODKINSON. 249serp53 mutation in the serum of black southern African patients with hepatocellular carcinomaJournal of Gastroenterology and Hepatology 2005; 20(8) doi: 10.1111/j.1440-1746.2005.03951.x
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Paul W. Ewald, Holly A. Swain Ewald. Infection, mutation, and cancer evolutionJournal of Molecular Medicine 2012; 90(5) doi: 10.1007/s00109-012-0891-2
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Jinmei Zhang, Yuan Yuan, Shuxia Gao, Xue Zhao, Hong Li. Diagnostic Performance of Circulating Cell-Free Dna for Hepatocellular Carcinoma: A Systematic Review and Meta-AnalysisBiomarkers in Medicine 2021; 15(3) doi: 10.2217/bmm-2020-0334
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Jian Zhou, Ao Huang, Xin-Rong Yang. Liquid Biopsy and its Potential for Management of Hepatocellular CarcinomaJournal of Gastrointestinal Cancer 2016; 47(2) doi: 10.1007/s12029-016-9801-0
18
Michael Torbenson, MD, Rajesh Kannangai, MD, Susan Abraham, MD, Fikret Sahin, MD, PhD, Michael Choti, MD, Jianzhou Wand, PhD, MD. Concurrent Evaluation of p53, b-catenin, and a-Fetoprotein Expression in Human Hepatocellular CarcinomaAmerican Journal of Clinical Pathology 2004; 122(3) doi: 10.1309/YH0H-3FKY-M4RM-U1JF
19
Jingjing Jiao, Weibo Niu, Ying Wang, Keith Baggerly, Yuanqing Ye, Xifeng Wu, Dewitt Davenport, Jose Luis Almeda, Monica M. Betancourt-Garcia, R. Armour Forse, Heather L. Stevenson, Gordon P. Watt, Joseph B. McCormick, Susan P. Fisher-Hoch, Laura Beretta. Prevalence of Aflatoxin-Associated TP53R249S Mutation in Hepatocellular Carcinoma in Hispanics in South TexasCancer Prevention Research 2018; 11(2) doi: 10.1158/1940-6207.CAPR-17-0235-AT
20
Kailas D Datkhile, Rashmi Gudur, Madhavi N Patil, Anand Gudur. Interactive Association of XRCC1, XRCC2, XRCC3, and TP53 Gene Polymorphisms With Gastrointestinal Cancer Risk: Insights From a Hospital-Based Case-Control StudyCureus 2024;  doi: 10.7759/cureus.61921
21
Jian-Guo Chen, Yuan-Rong Zhu, Geng-Sun Qian, Jin-Bing Wang, Jian-Hua Lu, Thomas W. Kensler, Lisa P. Jacobson, Alvaro Muñoz, John D. Groopman. Fifty Years of Aflatoxin Research in Qidong, China: A Celebration of Team Science to Improve Public HealthToxins 2025; 17(2) doi: 10.3390/toxins17020079
22
Fernanda Magri de Carvalho, Thiago de Almeida Pereira, Patrícia Lofego Gonçalves, Robson Dettmann Jarske, Fausto Edmundo Lima Pereira, Iuri Drumond Louro. Hepatocellular carcinoma and liver cirrhosis TP53 mutation analysis reflects a moderate dietary exposure to aflatoxins in Espírito Santo State, BrazilMolecular Biology Reports 2013; 40(8) doi: 10.1007/s11033-013-2587-2
23
Yunlong Cui, Hua Li, Hongjie Zhan, Tao Han, Yixuan Dong, Caijuan Tian, Yixian Guo, Fang Yan, Dong Dai, Pengfei Liu. Identification of Potential Biomarkers for Liver Cancer Through Gene Mutation and Clinical CharacteristicsFrontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.733478
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Xiao-mo Wu, Jing-geng Fu, Wang-zhong Ge, Jiang-yan Zhu, Jun-yong Wang, Wei Zhang, Wei Qian, Ke-ke Huo. Screen p53 mutations in hepatocellular carcinoma by FASAY: A novel splicing mutationJournal of Zhejiang University SCIENCE B 2007; 8(2) doi: 10.1631/jzus.2007.B0081
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Xinghua Huang, Guoqing Ji, Yanhua Wu, Bo Wan, Long Yu. LAMA4, highly expressed in human hepatocellular carcinoma from Chinese patients, is a novel marker of tumor invasion and metastasisJournal of Cancer Research and Clinical Oncology 2008; 134(6) doi: 10.1007/s00432-007-0342-6
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Yan Liu, Chung-Chou H. Chang, Gary M. Marsh, Felicia Wu. Population attributable risk of aflatoxin-related liver cancer: Systematic review and meta-analysisEuropean Journal of Cancer 2012; 48(14) doi: 10.1016/j.ejca.2012.02.009
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M. Fleischhacker, B. Schmidt. Circulating nucleic acids (CNAs) and cancer—A surveyBiochimica et Biophysica Acta (BBA) - Reviews on Cancer 2007; 1775(1) doi: 10.1016/j.bbcan.2006.10.001
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Klaus Jung, Michael Fleischhacker, Anja Rabien. Cell-free DNA in the blood as a solid tumor biomarker—A critical appraisal of the literatureClinica Chimica Acta 2010; 411(21-22) doi: 10.1016/j.cca.2010.07.032
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Y.M. Dennis Lo, Rossa W.K. Chiu. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics2012;  doi: 10.1016/B978-1-4160-6164-9.00045-7
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Kabir Mody, Sean P. Cleary. A Review of Circulating Tumor DNA in Hepatobiliary MalignanciesFrontiers in Oncology 2018; 8 doi: 10.3389/fonc.2018.00212
31
Sherif A. El-Kafrawy, Mohamed Abdel-Hamid, Mai El-Daly, Ola Nada, Alaa Ismail, Sameera Ezzat, Soheir Abdel-Latif, Amany Abdel-Hamid, Peter G. Shields, Christopher Loffredo. p53 Mutations in hepatocellular carcinoma patients in EgyptInternational Journal of Hygiene and Environmental Health 2005; 208(4) doi: 10.1016/j.ijheh.2005.02.002
32
Katarzyna Szymañska, Jian-Guo Chen, Yan Cui, Yun Yun Gong, Paul Craig Turner, Stéphanie Villar, Christopher Paul Wild, Donald Maxwell Parkin, Pierre Hainaut. TP53 R249S Mutations, Exposure to Aflatoxin, and Occurrence of Hepatocellular Carcinoma in a Cohort of Chronic Hepatitis B Virus Carriers from Qidong, ChinaCancer Epidemiology, Biomarkers & Prevention 2009; 18(5) doi: 10.1158/1055-9965.EPI-08-1102
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Rufina Igetei, Jesse A. Otegbayo, Dennis A. Ndububa, Olufunmilayo A. Lesi, Chiaka I. Anumudu, Pierre Hainaut, Emmanuelle Gormally. Detection of p53 codon 249 mutation in Nigerian patients with hepatocellular carcinoma using a novel evaluation of cell-free DNAAnnals of Hepatology 2008; 7(4) doi: 10.1016/S1665-2681(19)31834-4
34
Jingjing Jiao, Jessica I. Sanchez, Erika J. Thompson, Xizeng Mao, Joseph B. McCormick, Susan P. Fisher-Hoch, P. Andrew Futreal, Jianhua Zhang, Laura Beretta. Somatic Mutations in Circulating Cell-Free DNA and Risk for Hepatocellular Carcinoma in HispanicsInternational Journal of Molecular Sciences 2021; 22(14) doi: 10.3390/ijms22147411
35
Gabriel D. Dakubo. Cancer Biomarkers in Body Fluids2017;  doi: 10.1007/978-3-319-48360-3_8
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S. Saleem, Z. A. Abbasi, A. Hameed, N. R. Qureshi, M. A. Khan, A. Azhar. Novel p53 codon 240 Ser > Thr coding region mutation in the patients of oral squamous cell carcinoma (OSCC)Tumor Biology 2014; 35(8) doi: 10.1007/s13277-014-2062-2
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HORST H. SCHLECHTE, CORNELIA STELZER, SABINE WEICKMANN, MICHAEL FLEISCHHACKER, GUNTRAM SCHULZE. TP53 Gene in Blood Plasma DNA of Tumor PatientsAnnals of the New York Academy of Sciences 2004; 1022(1) doi: 10.1196/annals.1318.011
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V. B. Weeda, D. C. Aronson, J. Verheij, W. H. Lamers. Is hepatocellular carcinoma the same disease in children and adults? Comparison of histology, molecular background, and treatment in pediatric and adult patientsPediatric Blood & Cancer 2019; 66(2) doi: 10.1002/pbc.27475
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K. Pandima Devi, B. Sivamaruthi, PV Kiruthiga, S. Karutha Pandian. Study of p53 codon 72 polymorphism and codon 249 mutations in Southern India in relation to age, alcohol drinking and smoking habitsHuman & Experimental Toxicology 2010; 29(6) doi: 10.1177/0960327109354938
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Ying-Hsiu Su, Amy K. Kim, Surbhi Jain. Liquid biopsies for hepatocellular carcinomaTranslational Research 2018; 201 doi: 10.1016/j.trsl.2018.07.001